CAS: 1636-34-6; 2,3-Diphenylbutane-2,3-Diol

相似化合物

52340-78-0 2325-10-2 579-43-1

上下游产品

tetrahydro-2-phenylfuran hexane propyl sodium methyl magnesium iodide 2,3-diphenyl-1,3-butadiene 3-methyl-2-phenyl-1H-indene 2-methyl-1,2-diphenyl-propan-1-one 3,3-diphenylbutan-2-one

专利信息

专利号:US-4665257-A
优先权日:1986-10-20
标 题 :Facile, high yield synthesis of 2,3-diphenyl-1,3-butadiene
发明人：BENTLEY JAMES H
权利人:US ARMY
摘要:A high yield, four step synthesis process is disclosed for producing the omer, 2,3-diphenyl-1,3-butadiene, wherein in step 1 acetophenone pinacol is produced from the dimerization of acetophenone in 96% yield; in step 2 acetophenone pinacol is reacted with triethoxymethane and benzoic acid to produce 2,3-diphenyl-2-butene in about 88-96% yield. The 2,3-diphenyl-2-butene and N-bromosuccinimide (NBS) are reacted together in step 3 in an ultra violet reactor and in a CCl 4 reaction solvent to produce in about 92% yield, the dibromo compound, 1,4-dibromo-2,3-diphenyl-2-butene. In step 4, 1,4-dibromo-2,3-diphenyl-2-butene is converted to the desired monomer in about 86% yield by reacting with NaI under refluxing conditions for about 90 minutes in a hot acetone solution. The monomer 2,3-diphenyl-1,3-butadiene is recovered in hexane, shaken (in the order listed) with water solutions of NaHSO 3 , NaHCO 3 , and pure water, dried over CaCl 2 , and the hexane is spun off. The residue is then recrystallized from hot methyl alcohol by the addition of water. The crystals which are air dried should be refrigerated as soon as possible to prevent spontaneous polymerization.

专利号:US-8022235-B2
优先权日:2007-06-01
标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
发明人：PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells.

专利号:CN-114108014-A
优先权日:2020-08-28
标 题:A method for the synthesis of pinacol by selective electroreduction coupling of carbonyl compounds mediated by active hydrogen in water

专利号:US-2009018357-A1
优先权日:2007-06-01
标题:Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use

专利号:WO-2008150439-A1
优先权日:2007-06-01
标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use