9-蒽甲酸置于4-二甲氨基吡啶,Sodium Tetrahydroborate,十六烷基三甲基溴化铵,N,N'-二环己基碳二亚胺体系中,用 二氯甲烷,水,乙腈 用作溶剂,化学反应生成9-蒽醇 参考文献:Efficient And Simple Nabh4 Reduction Of Esters At Cationic Micellar Surface 标题:Efficient And Simple Nabh4 Reduction Of Esters At Cationic Micellar Surface 摘要:A Simple,Efficacious,And Biocompatible Methodology For Reducing Esters With Sodium Borohydride At An Aqueous Cationic Micellar Surface Under Ambient Conditions Has Been Developed. The Present Method Holds Promise For Future Use In Selective Functional Group Reduction And Stereocontrolled Alcohol Synthesis. Doi:10.1021/ol0481176
专利号:US-2012029226-A1 优先权日:2009-02-06 标题:Method for the synthesis of chiral alpha-aryl propionic acid derivatives 发明人:KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE 权利人:KAPTEIN BERNARDUS; VLIEG ELIAS; NOORDUIN WILLEM LIEUWE 摘要:The present invention provides a method for the synthesis of optically pure α-aryl propionic acid derivatives comprising subjecting the corresponding racemic α-aryl propionic acid derivatives to high sheer or impact forces, such as grinding.
专利号:US-11034664-B1 优先权日:2020-05-11 标题 :Synthesis of cyclic carbonate monomers 发明人:PARK NATHANIEL H; HEDRICK JAMES L; PIUNOVA VICTORIA A; ARRECHEA PEDRO; ERDMANN TIM 权利人:IBM 摘要:Techniques regarding the synthesis of cyclic carbonate monomers are provided. For example, one or more embodiments described herein can comprise a method, which can include cyclizing a functionalized diol monomer with N,N′-carbonyldiimidazole, wherein the cyclizing produces a cyclic carbonate monomer and an imidazole carbamate. The method can also include activating the imidazole carbamate with an acid, wherein the activating promotes cyclization of the imidazole carbamate into the cyclic carbonate monomer.
专利号:US-8268936-B2 优先权日:2005-01-04 标题:Synthesis of hybrid block copolymers and uses thereof 发明人:BREITENKAMP KURT; SILL KEVIN N 权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC 摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
专利号:US-2012196989-A1 优先权日:2005-02-11 标题:Synthesis of homopolymers and block copolymers 发明人:BREITENKAMP KURT; SILL KEVIN N 权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC 摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
专利号:US-9676904-B2 优先权日:2011-12-08 标 题:Metal alkoxide complex, catalyst composition, and production method of polycaprolactone or polylactide 发明人:CUI DONGMEI; LIU XINLI; LIU BO; LI SHIHUI; LIU DONGTAO; WU CHUNJI 权利人:CUI DONGMEI; LIU XINLI; LIU BO; LI SHIHUI; LIU DONGTAO; WU CHUNJI; CHANGCHUN INST APPLIED CHEMISTRY CAS 摘要:The invention provides a metal alkoxide complex of Formula (I), wherein X, M, R1, R2, R3, m, n, y and z are as defined in the Description. The invention also provides a catalyst composition comprising the metal alkoxide complex and a hydroxy-containing compound, wherein the molar ratio of the metal alkoxide complex to the hydroxy-containing compound is 1:0.1-1000. The invention also provides a production method of poly-ε-caprolactone or polyactide, wherein an ε-caprolactone monomer or a lactide monomer is reacted in the presence of the metal alkoxide complex or catalyst composition to obtain poly-ε-caprolactone or polylactide. The metal alkoxide complex and the catalyst composition thereof can be used to catalyze the synthesis of poly-ε-caprolactone or polylactide with a high efficiency. The molecular weight of polycaprolactone or polylactide can be controlled by the molar ratio of the metal alkoxide complex and the hydroxy-containing compound, and is adjustable in the range of 1000-600,000, and wherein the molecular weight distribution is from 1.03 to 1.50.n n[X n-m M(OCR 1 R 2 R 3 ) m ] y .(organic solvent) z   (I)
专利号:US-7470783-B2 优先权日:1995-12-15 标 题 :Photocleavable protecting groups and methods for their use 发明人:MCGALL GLENN H; NAM NGO Q; RAVA RICHARD P 权利人:AFFYMETRIX INC 摘要:Novel compounds are provided which are useful as linking groups in chemical synthesis, preferably in the solid phase synthesis of oligonucleotides and polypeptides. These compounds are generally photolabile and comprise protecting groups which can be removed by photolysis to unmask a reactive group. The protecting group has the general formula Ar—C(R 1 )(R 2 )—O—C(O)-wherein:n Ar is an optionally substituted fused polycyclic aryl or heteroaromatic group or a vinylogous derivative thereof; R 1 and R2 are independently H, optionally substituted alkyl, alkenyl or alkynyl, optionally substituted aryl or optionally substituted heteroaromatic, or a vinylogous derivative of the foregoing; and X is a leaving group, a chemical fragment linked to Ar—C(R 1 )(R 2 )—O—C(O)— via a heteroatom, or a solid support; provided that when Ar is 1 -pyrenyl and R 1 and R 2 are H, X is not linked to Ar—C(R 1 )(R 2 )—O—C(O)— via a nitrogen atom. Preferred embodiments are those in which Ar is a fused polycyclic aromatic hydrocarbon and in which the substituents on Ar, R 1 and R 2 are electron donating groups. A particularly preferred protecting group is the “PYMOCâ€? protecting group, pyrenylmethyloxycarbonyl, where Ar is pyrenyl and R 1 and R 2 are H. nn Also provided is a method of forming, from component molecules, a plurality of compounds on a support, each compound occupying a separate predefined region f the support, using the protected compounds described above.
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合成参考文献
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