CAS: 1265919-24-1; Ethyl 2-(((3Ar,4S,6R,6As)-6-Amino-2,2-Dimethyltetrahydro-3Ah-Cyclopenta[d][1,3]Dioxol-4-yl)Oxy)Acetate

相似化合物

1402149-98-7 1215268-15-7 274693-55-9

📜(3Ar,4S,6R,6As)-6-氨基四氢-2,2-二甲基-4H-环戊烯并-1,3-二氧杂环戊烷-4-醇置于palladium 10% On Activated Carbon 氢气,Sodium Hydride,Sodium Carbonate体系中,用 四氢呋喃,甲醇,水,N,N-二甲基甲酰胺 用作溶剂,化学反应 7.33H,反应生成替格瑞洛杂质
参考文献: Cyclopropyl Modulators Of P2Y12 Receptor[fr] Modulateurs Cyclopropylés Du Récepteur P2Y12
标题: Cyclopropyl Modulators Of P2Y12 Receptor[fr] Modulateurs Cyclopropylés Du Récepteur P2Y12

专利信息

专利号:US-9469614-B2
优先权日:2011-10-27
标 题:Synthesis of triazolopyrimidine compounds
发明人：ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.

专利号:US-9278972-B2
优先权日:2011-12-23
标题 :Synthesis of triazolopyrimidine compounds
发明人：MARAS NENAD; GAZIC SMILOVIC IVANA; STERK DAMJAN
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.

专利号:US-9221829-B2
优先权日:2011-09-14
标题:Synthesis of triazolopyrimidine compounds
发明人：MARAS NENED; ZUPANCIC BORUT
权利人:MARAS NENED; ZUPANCIC BORUT; LEK PHARMACEUTICALS
摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of Ticagrelor (TCG).

专利号:EP-2570405-A1
优先权日:2011-09-14
标题:Synthesis of Triazolopyrimidine Compounds
权利人:LEK PHARMACEUTICALS
摘要:The present invention relates to the filed of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives, suitable for the preparation of ticagrelor (TGC)

专利号:WO-2017072790-A1
优先权日:2015-10-26
标 题 :An improved process for synthesis of ticagrelor
发明人：RAO RAMAKRISHNA; NANDIPATI RAMADEVI; SHEWALKAR MUKESH PADMAKAR; BOGIREDDY VEERABHADRA REDDY
权利人:AVRA LABORATORIES PVT LTD
摘要:The present invention discloses an improved and cost effective process for preparation of Ticagrelor in good yield and purity. The invention further discloses novel Polymorphic Form of Ticagrelor and its process for preparation thereof.

专利号:US-2015005498-A1
优先权日:2011-09-14
标 题 :Synthesis of Triazolopyrimidine Compounds