CAS: 1193-24-4; 4,6-Dihydroxypyrimidine

相似化合物

51953-18-5 5270-94-0 106615-61-6

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CAS号108-59-8 丙二酸二甲酯 | CAS号77287-34-4 甲亚胺酸 | CAS号105-53-3 丙二酸二乙酯 | CAS号143-37-3 acetamidine | CAS号108-13-4 丙二酰胺 | CAS号109-94-4 甲酸乙酯 | CAS号141-52-6 乙醇钠 | CAS号463-52-5 formamidine | CAS号4316-94-3 4-氨基-6-氯-5-硝基-嘧啶 | CAS号4316-93-2 4,6-二氯-5-硝基嘧啶 | CAS号5305-40-8 4,6-二氯-5-嘧啶甲醛 | CAS号1193-21-1 4,6-二氯嘧啶 | CAS号1780-27-4 4,5,6-三氯嘧啶 | CAS号2164-83-2 5-硝基-4,6-二羟基嘧啶 | CAS号15726-38-2 5-溴-4,6-二羟基嘧啶 | CAS号53925-27-2 2-甲基-5-硝基-4,6-嘧啶二醇 | CAS号59025-32-0 2,4,6(1H,3H,5H)...

丙二酸二甲酯 以 水 用作溶剂,以74.8%的收率获得4,6-二羟基嘧啶
参考文献:Chemical Process
标题:Chemical Process
摘要:制备4,6-二羟基嘧啶的过程包括以下步骤:A) 在roh溶剂中接触甲酰胺,公式为rom的烷氧基化合物和公式为ch.Sub.2(co.Sub.2R).Sub.2的马隆酸酯; B) 向步骤(a)的产物中加入水; C) 从步骤(b)的产物中去除几乎所有的roh溶剂; 和d) 酸化步骤(c)的产物,其中r是c.Sub.1-4烷基,M是碱金属.

专利信息

专利号:US-2002042514-A1
优先权日:2000-06-26
标 题 :Synthesis of chlorinated pyrimidines
发明人：DOYLE TIMOTHY JOHN; WEHRENBERG PETER KARL; STANDEN MICHAEL CHARLES HENRY
摘要:A facile process for the preparation of 4,6-dichloropyrimidine is provided, which utilizes quaternary ammonium salts or quaternary phosphonium salts as catalysts for the reaction of, for example, 4,6-dihydroxypyrimidine or 4-chloro-6-methoxypyrimidine with phosgene.

专利号:US-2006115536-A1
优先权日:2004-11-12
标 题 :Glycerin based synthesis of silver nanoparticles and nanowires
发明人：YACAMAN MIGUEL J; ELECHIGUERRA JOSE L; BURT JUSTIN L; MORONES JOSE R; LOPEZ LETICIA L
权利人:UNIV TEXAS
摘要:The present invention includes compositions and methods for the production of noble metal nanoparticles and nanowires conjugated to polyols or polymers. The present invention allows the incorporation of noble metal nanoparticles to a wide range of products such as body care products to exploit the biocidal properties of silver nanoparticles against bacteria, viruses and fungi.

专利号:WO-2012127472-A1
优先权日:2011-03-22
标题:Process and intermediates for the preparation of preladenant and related compounds
发明人：MAROM EHUD; MIZHIRITSKII MICHAEL; RUBNOV SHAI
权利人:MAPI PHARMA LTD; MAROM EHUD; MIZHIRITSKII MICHAEL; RUBNOV SHAI
摘要:The present invention describes processes for the synthesis of 2-(furan-2-yl)-7-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-l-yl] ethyl]-7H-pyrazolo[ 4,3-e ][1,2,4]- triazolo[1,5c] pyrimidin-5-amine (Preladenant) represented by the structure of formula (1 ), and solvates and salts thereof, especially salts with pharmaceutically acceptable acids. The process of the present invention is useful not only for Preladenant production, but also for the preparation of other biologically active compounds of general formula (17), such as A2a receptor antagonists used for the treatment of central nervous system diseases, among others. The present invention further relates to certain intermediates formed in such processes.

专利号:US-2005027120-A1
优先权日:2003-06-02
标 题 :Method for the synthesis of amides and related products from esters or ester-like compounds
发明人：GOJON-ZORRILLA GABRIEL
权利人:REACTIMEX S A DE C V
摘要:A versatile, eco-friendly, and efficient method for the convenient conversion of esters and ester-like compounds into amides, peptides, carbamates, ureas, oxamides, oxamates, hydrazides, oxazolidinones, pyrazolones, oxazolidinediones, barbituric acids, and other molecules containing one or more OCN moieties in the presence of a diol or polyol is disclosed.

专利号:US-3965125-A
优先权日:1971-02-08
标题:Synthesis of certain bis(phthalic anhydrides)
发明人：MEYERS ROBERT A
权利人:TRW INC
摘要:Monomeric high molecular weight dianhydrides or tetraacids can be produced by the nucleophilic coupling of a halo substituted phthalimides acid and an aliphatic or aromatic compound having polyfunctional groups capable of reacting with the halo moiety of the phthalinide followed by hydrolysis and dehydration. Specifically, 4-chlorophthalate sodium salt is converted to an imide to reduce side reactions with the carboxylic acid groups prior to reaction with 4,4'-disodiumdiphenylene oxide sulfone or 2,2-di (4-sodium phenoxide) propane. After the reaction of the imide and the sulfone or propane compounds, the diimide formed is converted to the corresponding dianhydride.

专利号:US-6608199-B2
优先权日:2000-07-07
标题 :Synthesis of chlorinated pyrimidines
发明人：DOYLE TIMOTHY JOHN; BENKE ALAN HENRY; WEHRENBERG PETER KARL; NADY LOUIE AKOS
权利人:SYNGENTA LTD
摘要:The invention provides a process for synthesizing chlorinated pyrimidines. The process includes reacting imidoyl chloride compounds with phosgene (COCl2). The imidoyl chloride compounds can be supplied as starting materials or can be produced by reacting organic amides with phosgene or reacting organic nitrites with hydrogen chloride. The chlorinated pyrimidines, such as 4,6-dichloropyrimidine, can be used to synthesize other compounds useful in a variety of compositions, such as fungicides, pesticides, and pharmaceuticals.