CAS: 10386-27-3; 2-Bromoisonicotinonitrile

相似化合物

118289-17-1 29840-73-1 66572-56-3

上下游产品

CAS号14305-17-0 2-溴吡啶-N-氧化物 | CAS号52092-43-0 2-溴-4-硝基吡啶-N-氧化物 | CAS号7598-35-8 4-氨基-2-溴吡啶 | CAS号151-50-8 氰化钾 | CAS号100004-94-2 2-(间甲苯基)异烟酸 | CAS号22282-72-0 2-羟基异烟酸 | CAS号98436-74-9 2-乙烯基异烟腈

2-溴-4-硝基吡啶氮氧化物置于ammonium Hydroxide,硫酸,Copper(II) Sulfate,Iron(II) Sulfate,Sodium Nitrite体系中,化学反应生成2-溴-4-氰基吡啶
参考文献:Talik,Roczniki Chemii,1957,Vol. 31,P. 569,574
标题:Talik,Roczniki Chemii,1957,Vol. 31,P. 569,574

专利信息

专利号:US-11739065-B2
优先权日:2016-06-13
标题 :FXR (NR1H4) modulating compounds
发明人：BLOMGREN PETER A; CURRIE KEVIN S; GEGE CHRISTIAN; KROPF JEFFREY E; XU JIANJUN
权利人:GILEAD SCIENCES INC
摘要:The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

专利号:US-9751874-B2
优先权日:2014-12-17
标题:Hydroxy containing FXR (NR1H4) modulating compounds
发明人：GEGE CHRISTIAN; KINZEL OLAF; KREMOSER CLAUS; SCHMITT AARON C
权利人:GILEAD SCIENCES INC
摘要:The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.