CAS: 97-27-8; 2,2-Dichloro-N-[(2,4-Dichlorophenyl)Methyl]-N-(2-Hydroxyethyl)Acetamide
该化合物是一种属于磺酰胺类别的化学化合物,主要用作抗糖尿病剂,其特点是能够刺激胰腺分泌胰岛素,从而帮助降低2型糖尿病患者血液中的血糖含量,该化合物一般是白色的,是白外晶粉,在水和有机溶剂中可溶解.氯乙酰胺具有中度的分子重量,在标准条件下呈现相对稳定的结构.其行动机制涉及对胰腺乙型细胞的特定受体具有约束力,这增加了胰岛素的释放,以应对高血糖含量.此外,这可能对外围胰岛素敏感度产生一些影响.与许多药物一样,必须考虑潜在的副作用,其中可包括低血糖和胃肠紊乱.适当的剂量和监测对于在糖尿病管理中的有效和安全使用至关重要.
- 英文名称2,2-Dichloro-N-[(2,4-Dichlorophenyl)Methyl]-N-(2-Hydroxyethyl)Acetamide
- 中文名称氯倍他胺
- IUPAC名称2,2-Dichloro-N-2,4-dichlorobenzyl-N-2-hydroxyethyl-acetamide
- 其它别名Acetamide,2,2-dichloro-N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)- (6CI,7CI,8CI); 2,2-Dichloro-N-(2,4-dichlorobenzyl)-N-2-hydroxyethylacetamide; Chlorbetamide; Clorbetamida; Diantil; Dichloro-N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)acetamide; Mantomide; N-(2,4-Dichlorobenzyl)-N-(2-hydroxyethyl)dichloroacetamide; Pontalin; a,a-Dichloro-N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)acetamide
- CAS编号97-27-8
- MFCD编号:MFCD00864650
- FDA UNII编号:3S489RFX0J
- 分子式:C11H11Cl4NO2分子量:331.025
- 产品CID: 2020734
- 产品分类有机原料 → 苯类化合物 → 苯和取代衍生物
物理性质
MSDS等安全信息
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海关参考信息
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2903919090-氯苯
2912110000-甲醛
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专利信息
专利号:US-5001294-A
优先权日:1988-10-31
标 题 :Synthesis of diaryl alkenes
发明人：HAY ALLAN S
权利人:HAY ALLAN S
摘要:Aromatic alkenes, especially diarylbutadienes are produced in a simple economic process by reaction of an anil with an organic compound having a non-aromatic unsaturated system conjugated with an aromatic system, and a terminal methyl group pendent from the non-aromatic unsaturated system; in particular the organic compound is a propenyl-substituted aromatic compound.
专利号:US-2006004188-A1
优先权日:2000-09-29
标 题:Intermediates and the synthesis of modified carbocyanine dyes and their conjugates
专利号:US-7892297-B2
优先权日:2003-08-12
标题 :Cyanin-type compounds having an alkynyl linker arm
发明人：CAPUTO GIUSEPPE
权利人:CYANINE TECHNOLOGIES S P A
摘要:Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.
专利号:US-7566790-B2
优先权日:2000-09-29
标 题 :Intermediates and the synthesis of modified carbocyanine dyes and their conjugates
专利号:CN-106458847-A
优先权日:2014-05-29
标 题:Synthesis of Novel Diamine and Its Liquid Crystal Alignment Agent
专利号:US-9110069-B2
优先权日:2009-01-15
标题:Luminescent compounds
发明人：TERPETSCHNIG EWALD A; PATSENKER LEONID D; MARKOVA LARYSA; FEDYUNYAEVA IRYNA A; KOLOSOVA OLGA S; OBUKHOVA OLENA M; TATARETS ANATOLIY
权利人:SETA BIOMEDICALS LLC
摘要:Dyes and photoluminescent compounds based on polymethine dyes that contain at least one alkyl-phosphonate or substituted alkyl-phosphonate group, including the synthetic precursors, methods of synthesis, and applications thereof. Certain embodiments include heterocyclic ring systems and polymethine linkages selected such that the resulting polymethine dye is a cyanine dye, a merocyanine dye or a styryl dye.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: FERNANDO PV. Treatment of hookworm with chlorbetamide, bephenium and tetrachlorethylene. J Trop Med Hyg. 1961 Jul;64:180-3. Portuguese.
合成参考文献
摘要:Antibiotics and Chemotherapy, 4(554), 1954
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