CAS: 6939-95-3; 1-(3-Chlorophenyl)Ethanol

上下游产品

acetaldehyde (3-chlorophenyl)magnesium bromide methyl magnesium iodide m-Chlorobenzaldehyde 3'-Chloroacetophenone 1-chloro-3-(1-chloroethyl)benzene 1-(m-Chlorphenyl)aethyl-diphenylphosphinat 1-(3-chlorophenyl)ethyl vinyl ether

📜3-氯苯乙烯置于水,氢气体系中,150.0 °C,4.0 Mpa 条件下,反应 6.0H,反应生成 1-(3-氯苯基)乙醇
参考文献:用于烯烃和环氧烷烃在 Co-N 受阻路易斯对表面上水合的氢催化酸转化
标题:用于烯烃和环氧烷烃在 Co-N 受阻路易斯对表面上水合的氢催化酸转化
摘要:氢气 (H 2) 广泛用作许多加氢反应的还原剂;然而,它尚未被认为是固体表面活性位点酸转化的催化剂.在这里,我们通过酸碱位点的转化机制报告了烯烃(如苯乙烯和环烯烃)和环氧烷烃在单原子共分散氮掺杂碳(co-Nc)上的 H 2促进水合.具体而言,每微摩尔酸,Co-Nc 的特定催化活性和选择性优于经典固体酸(酸性沸石和树脂),而水合催化不在氮气氛下进行.详细研究表明,H 2可以在 Co-N 键上杂解形成 H δ−-co-n-h δ+然后通过 H2O 介导的路径转化为 Oh δ−-co-n-h δ+伴随着 H 2 的反应生成,这显着降低了水合反应的活化能.这项工作不仅为水合反应提供了一种新的催化方法,而且还消除了加氢和酸催化之间的概念障碍.
DOI:10.1021/jacs.1C08259

专利信息

专利号:US-2023151034-A1
优先权日:2020-03-17
标题:Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
发明人：JACOBSON IRINA C; LEE SAM SK; PIZARRO NOVOA JUAN CARLOS
权利人:COCRYSTAL PHARMA INC
摘要:Peptidomimetic N5-methyl-N2-(nonanoyl-L-leucyl)-L-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds for use in methods of inhibiting the replication of noroviruses and coronaviruses in a biological sample or patient, for use in reducing the amount of noroviruses or coronaviruses in a biological sample or patient, and for use in treating norovirus and coronavirus in a patient, comprising administering to said biological sample or patient a safe and effective amount of a compound represented by formulae I or II, or a pharmaceutically acceptable salt thereof. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. page 99 to page 271; examples 1 to 3; compounds A1 to A104 and B1 to B66; tables A to E).

专利号:CN-108821931-B
优先权日:2018-08-08
标 题 :A kind of catalytic oxidation synthesis method of benzoic acid compounds