CAS: 486-84-0; 1-Methyl-9H-Pyrido[3,4-B]Indole

结构式图片

相似化合物

20127-63-3 83911-48-2 244-63-3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号525-41-7 Harmalane | CAS号5159-20-6 1-methyl-2-(tol... | CAS号2506-10-7 1-甲基-1H,2H,3H,4... | CAS号75-91-2 叔丁基过氧化氢 | CAS号244-63-3 9H-吡啶[3,4-b]吲哚 | CAS号1016-47-3 N-乙酰基色胺 | CAS号127-19-5 N,N-二甲基乙酰胺(DMAC) | CAS号82980-12-9 3-ethenyl-1-phe... | CAS号5470-37-1 1-甲基-1,2,3,4-四氢... | CAS号15071-56-4 5-甲氧基铁屎米酮 | CAS号244-63-3 9H-吡啶[3,4-b]吲哚 | CAS号139332-12-0 2,3-diethyl-12H... | CAS号102206-91-7 1-methyl-9H-pyr... | CAS号102207-02-3 1-甲基-8-硝基-9h-吡啶... | CAS号38314-91-9 1-methyl-6-nitr... | CAS号138428-34-9 9H-吡啶并[3,4-b]吲哚... | CAS号20127-63-3 苦木碱C | CAS号18813-71-3 6-溴-1-甲基-9h-吡啶并... | CAS号2521-07-5 9-甲基-β-咔啉

合成工艺路线路线简述

    📜育亨酸 反应生成 哈尔满碱
    参考文献:Warnat,Chemische Berichte,1927,Vol. 60,P. 1121
    标题:Warnat,Chemische Berichte,1927,Vol. 60,P. 1121

    海关参考信息

    专利信息


    专利号:US-12275733-B2
    优先权日:2016-11-07
    标 题:Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
    发明人:GRETZKE DIRK; RITZELER OLAF; HEINELT UWE; WEHNER VOLKMAR; SCHMIDT FRIEDEMANN
    权利人:SANOFI SA
    摘要:The present invention relates to 8-aryl-substituted and 8-heteroaryl-substituted 9H-pyrido[3,4-b]indoles of the formula (I), in which A, E, G, R1 to R6 and R10 are as defined in the claims, which stimulate chondrogenesis and cartilage matrix synthesis and can be used in the treatment of cartilage disorders and conditions in which a regeneration of damaged cartilage is desired, for example joint diseases such as osteoarthritis. The invention furthermore relates to processes for the synthesis of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.

    专利号:US-7192749-B2
    优先权日:2002-05-16
    标题 :Use of the repressor glxR for the synthesis of lysine in Corynebacterium glutamicum
    发明人:KLOPPROGGE CORINNA; ZELDER OSKAR; KROEGER BURKHARD; SCHROEDER HARTWIG; HAEFNER STEFAN; LEE HEUNG-SHICK
    权利人:BASF AG
    摘要:Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene of C. glutamicum and which can be obtained from SEQ ID NO:1 by inserting, deleting or substituting up to 20% of the amino acids.

    专利号:US-10590158-B2
    优先权日:2015-06-29
    标题:Total synthesis of shishijimicin A and analogs thereof
    发明人:NICOLAOU KYRIACOS C; LI RUOFAN; LU ZHAOYONG; SOHN TE-IK; WOODS JAMES; PITSINOS EMMANOUIL N
    权利人:UNIV RICE WILLIAM M
    摘要:In one aspect, the present disclosure provides shishijimicin analogs of the formula: wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, antibody drug conjugates of the compounds are also provided.

    专利号:US-9815694-B2
    优先权日:2013-10-16
    标 题 :Catalytic ammonia synthesis by transition metal molecular complexes
    发明人:PETERS JONAS C; ANDERSON JOHN S; CRUETZ SIDNEY E; RITTLE JONATHAN D
    权利人:CALIFORNIA INST OF TECHN
    摘要:This invention relates to molecular catalysts and chemical reactions utilizing the same, and particularly to catalysts and catalytic methods for reduction of molecular nitrogen. The molecular catalytic platform provided herein is capable of the facile reduction of molecular nitrogen under useful conditions such as room temperature or less and atmospheric pressure or less.

    专利号:US-8194868-B2
    优先权日:2003-05-08
    标 题:Loudspeaker system for virtual sound synthesis
    发明人:HORBACH ULRICH; CORTEEL ETIENNE
    权利人:HORBACH ULRICH; CORTEEL ETIENNE; HARMAN INT IND
    摘要:A sound system obtains a desired sound field from an array of sound sources arranged on a panel. The desired sound field allows a listener to perceive the sound as if the sound were coming from a live source and from a specified location. Setup of the sound system includes arranging a microphone array adjacent the array of sound sources to obtain a generated sound field. Arbitrary finite impulse response filters are then composed for each sound source within the array of sound sources. Iteration is applied to optimize filter coefficients such that the generated sound field resembles the desired sound field so that multi-channel equalization and wave field synthesis occur. After the filters are setup, the microphones may be removed.

    专利号:US-7790137-B2
    优先权日:2006-08-14
    标题:Metal telluride nanocrystals and synthesis thereof
    发明人:XIAO QIANGFENG; LU YUNFENG; ZHANG MINJUAN
    权利人:TOYOTA ENG & MFG NORTH AMERICA; UNIV TULANE
    摘要:A process for synthesizing a metal telluride is provided that includes the dissolution of a metal precursor in a solvent containing a ligand to form a metal-ligand complex soluble in the solvent. The metal-ligand complex is then reacted with a telluride-containing reagent to form metal telluride domains having a mean linear dimension of from 2 to 40 nanometers. NaHTe represents a well-suited telluride reagent. A composition is provided that includes a plurality of metal telluride crystalline domains (PbTe)1-x-y(SnTe)x(Bi2Te3)y  (I) having a mean linear dimension of from 2 to 40 nanometers inclusive where x is between 0 and 1 inclusive and y is between 0 and 1 inclusive with the proviso that x+y is less than or equal to 1. Each of the metal telluride crystalline domains has a surface passivated with a saccharide moiety or a polydentate carboxylate. A densified mass having a density of greater than 95% of the theoretical density includes a plurality of lead telluride, tin telluride, bismuth telluride, or a combination thereof of domains having a mean linear dimension of from 2 to 40 nanometers inclusive that have been subjected to hot isotactic pressing.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Glover V, Et, Al. β-Carbolines As Selective Monoamine Oxidase Inhibitors:In Vivo Implications
    [参考文献]: Louis Ed, Et, Al. Blood Harmane Concentrations And Dietary Protein Consumption In Essential Tremor. Neurology. 2005 Aug 9;65(3):391-6.
    [参考文献]: Musgrave If, Et, Al. Harmane Produces Hypotension Following Microinjection Into The Rvlm: Possible Role Of I(1)-Imidazoline Receptors. Br J Pharmacol. 2000 Mar;129(6):1057-9.
    [参考文献]: Umezawa K, Et, Al. Comutagenic Effect Of Norharman And Harman With 2-Acetylaminofluorene Derivatives. Proc Natl Acad Sci U S A. 1978 Feb;75(2):928-30.
    [参考文献]: Betty C Galarreta, Et Al. The Use Of Natural Product Scaffolds As Leads In The Search For Trypanothione Reductase Inhibitors. Bioorg Med Chem. 2008 Jul 15;16(14):6689-95.

    合成参考文献


    参考文献:10.18632/aging.100052
    摘要:Altmeyer M, Hottiger MO. Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging. Aging (Albany NY). 2009 May 20;1(5):458–69.
    参考文献:10.18632/aging.100081
    摘要:Richardson RB. Ionizing radiation and aging: rejuvenating an old idea. Aging (Albany NY). 2009 Nov 17;1(11):887–902.
    参考文献:10.1007/s00167-011-1605-y
    摘要:Wolterbeek N, Nelissen RGHH, Valstar ER. No differences in in vivo kinematics between six different types of knee prostheses. Knee Surgery, Sports Traumatology, Arthroscopy. 2011 Jul 15;20(3):559–64. doi: 10.1007/s00167-011-1605-y.
    参考文献:10.1136/bmj.d4065
    摘要:Husebo BS, Ballard C, Sandvik R, Nilsen OB, Aarsland D. Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial. BMJ. 2011 Jul 15;343():d4065.
    参考文献:10.4103/0974-2700.82224
    摘要:Papavramidis TS, Marinis AD, Pliakos I, Kesisoglou I, Papavramidou N. Abdominal compartment syndrome - Intra-abdominal hypertension: Defining, diagnosing, and managing. J Emerg Trauma Shock. 2011 Apr;4(2):279–91.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知