CAS: 40580-59-4; Guanadrel

上下游产品

N-(1,4-Dioxaspiro[4,5]dec-2-ylmethyl)-N',N''-bis(benzyloxycarbonyl)guanidine 1,4-dioxa-spiro[4.5]dec-2-ylmethyl-cyanamide 1,4-Dioxaspiro[4,5]dec-2-ylmethanamine N-(1,4-dioxaspiro[4,5]dec-2-ylmethyl)acetamide

📜1,4-二噁螺[4.5]癸烷-2-甲胺置于palladium On Activated Charcoal 氢气,三乙胺体系中,用 四氢呋喃,甲醇,氯仿 作为反应溶剂,20.0 °C,344.74 Kpa 条件下,反应 11.0H,反应生成 胍那决尔
参考文献:Synthesis Of Biologically Important Guanidine-Containing Molecules Using Triflyl-Diurethane Protected Guanidines
标题:Synthesis Of Biologically Important Guanidine-Containing Molecules Using Triflyl-Diurethane Protected Guanidines
摘要:
DOI:10.1055/s-1999-3653

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-RE41998-E
优先权日:1990-02-26
标题 :Compositions and methods of treatment of sympathetically maintained pain
发明人：CAMPBELL JAMES N
权利人:ARCLON THERAPEUTICS INC
摘要:Sympathetically maintained pain is treated topically by administering to the site where sympathetically maintained pain is present an α-1-adrenergic antagonist, α-2-adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic norepinephrine, known collectively as sympatholytic agents. Chemical formulas for several sympatholytic agents are given.

专利号:US-9556123-B2
优先权日:2004-07-19
标题:Synthesis of triethylenetetramines
发明人：JONAS MARCO; VAULONT IRENE; SOI ANTONIO; SCHMIDT GUNTHER
权利人:PHILERA NEW ZEALAND LTD
摘要:Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.

专利号:US-2006165683-A1
优先权日:2001-12-05
标题:Methods and compositions for control of bone formation via modulation of sympathetic tone
发明人：KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
权利人:KARSENTY GERARD; TAKEDA SHU; ELEFTERIOU FLORENT
摘要:This invention relates to methods for treatment, diagnosis and prevention of bone disease and comprises methods including measurement and modulation of sympathetic tone and leptin activity. Alteration of sympathetic tone in bone disease can be accomplished by decreasing or increasing leptin synthesis, leptin receptor synthesis, leptin binding to the leptin receptor, and leptin receptor activity. Alteration of sympathetic tone in bone disease can also be accomplished in the foregoing manner, in combination with traditional sympathetic nervous system agonists and/or antagonists, such as, but not limited to, a dopamine β hydroxylase antagonist or a β adrenergic antagonist for treatment or prevention of osteoporosis.

专利号:US-2020148647-A1
优先权日:2004-07-19
标题:Synthesis of Triethylenetetramines

专利号:KR-101513003-B1
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy compositions and applications