CAS: 39492-01-8; Ethyl 4-((6-Guanidinohexanoyl)Oxy)Benzoate

该化合物是一种主要因其作为蛋白抑制剂的作用而得到承认的合成化合物,被归类为麻痹蛋白抑制剂,并经常用于临床环境,以管理与过度蛋白性活动有关的条件,如胰腺炎.加贝氏体表现出各种精液蛋白的高度亲近性,包括试剂和激素,从而调节炎情反应和预防组织损伤.该化合物通常通过静脉注射进行,并已知其迅速开始作用.就其化学结构而言,加贝氏体含有一种碳柱,功能组群为与蛋白质的相互作用提供便利.它一般具有良好的作用,尽管潜在的副作用可能包括过敏反应或胃肠扰动.加贝氏体的药理学表明一种相对较短的半衰期,因此需要在治疗应用中谨慎地施用.总的来说,加贝氏体是管理与蛋白有关紊乱的重要药剂.

英文名称Ethyl 4-((6-Guanidinohexanoyl)Oxy)Benzoate
中文名称甲磺酸加贝酯
IUPAC名称ethyl 4-((6-guanidinohexanoyl)oxy)benzoate
其它别名Gabexate; p-Carbethoxyphenyl e-guanidine°Caproate; p-Carbethoxyphenyl e-guanidin°Caproate
CAS编号39492-01-8
MFCD编号:MFCD00867386
FDA UNII编号:4V7M9137X9
分子式:C16H23N3O4分子量:321.38
产品CID: 1406808
产品分类有机原料 → 无机酸酯

相似结构搜索
InChIKey: YKGYIDJEEQRWQH-UHFFFAOYSA-N
InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19)
计算化学: 氢键受体数5.0氢键供体数2.0可旋转键数11.0

MSDS等安全信息

警示词warning
危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
安全声明H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body

上下游产品

Ethyl 4-hydroxybenzoate ε-guanidin°Caproic acid

合成工艺路线路线简述

📜过氧化氢酶,6-胍基己酸盐酸盐置于吡啶,2-氯-1,3-二甲基氯化咪唑啉体系中,用二氯甲烷用作溶剂,化学反应 12.0H,以76%的收率获得甲磺酸加贝酯
参考文献:2-Chloro-1,3-Dimethylimidazolinium Chloride. 1. A Powerful Dehydrating Equivalent To Dcc
标题:2-Chloro-1,3-Dimethylimidazolinium Chloride. 1. A Powerful Dehydrating Equivalent To Dcc
摘要:2-Chloro-1,3-Dimethylimidazolinium Chloride (Dmc) (3) Can Act As A Powerful Dehydrating Agent,Replacing Dcc (1) Under Nearly Neutral Conditions. Its Application To Acylation And Dehydration Is Described.
Doi:10.1021/jo990210Y