CAS: 38444-76-7; 2,3',6-Trichloro-1,1'-Biphenyl
该化合物是一种氯化联苯化合物,其特点是联苯结构中存在三个氯原子,具体而言,氯替代成分位于二,三'和六个位置,联苯环中,该化合物是被称为多氯联苯(PCB)的更大类别化学品的一部分,这些化学品因其化学稳定性和绝缘性而在工业应用中广泛使用. 2,3',6-三氯联苯在室内温度上一般色素色素不及黄色固体,在水中溶解,但在有机溶剂中可溶解.众所周知,该化合物在环境中的持久性和生物体中潜在的生物累积性,引起了人们对其毒性和环境影响的关切.该化合物已经对其对人类健康和生态系统的影响进行了研究,因为与多氯联苯的接触与各种有害健康影响有关,包括内分泌干扰和致癌性.由于这些关切,许多国家对多氯联苯的使用进行了严格的管制或禁止.
- 英文名称2,3',6-Trichloro-1,1'-Biphenyl
- 中文名称2,3',6-三氯-1,1'-联苯
- IUPAC名称1,3-dichloro-2-(3-chlorophenyl)benzene
- 其它别名2,3',6-三氯联苯非标 35 Ug/ml Isooctane; 2,3',6-Trichlorobiphenyl
- CAS编号38444-76-7
- MFCD编号:MFCD00152899
- FDA UNII编号:K29N6Z59BC
- 分子式:C12H7Cl3分子量:257.54
- 产品CID: 1396594
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
相似化合物
37680-68-5 41464-41-9 33146-45-1物理性质
MSDS等安全信息
- GHS符号GHS07
- 警示词Warning
- 危险描述H302-H315-H319-H335
- 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
1,3-dichloro-2-iodobenzene 3-iod°Chlorobenzene合成工艺路线路线简述
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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