专利号:UA-77527-C2 优先权日:2002-06-20 标题:Benzoic acid derivatives as modulators of ppar alpha and ppar gamma, method of synthesis, pharmaceutical composition, intermediate
专利号:UA-77987-C2 优先权日:2001-12-19 标题:Substituted derivatives of phenylpropionic acid as agonists of peroxisome proliferators activated alpha receptor, method for synthesis, pharmaceutical composition, intermediate (variants)
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
专利号:US-7022676-B2 优先权日:2001-11-21 标题:Peptide having angiotensin converting enzyme inhibitory effect 发明人:TAMURA YOSHITAKA; MIYAKAWA HIROSHI; YAMADA AKIO; SAITO HITOSHI; KAWAGUCHI YASUSHI; OCHI HIROSHI; IDE TOMOKO; INOUE ERI 权利人:MORINAGA MILK INDUSTRY CO LTD 摘要:A peptide Met-Lys-Pro, which is obtained by chemical synthesis ot hydrolysis of casein, is used as the active ingredient of angiotensin converting enzyme inhibitors or hypotensive drugs.
参考文献:10.1523/jneurosci.5692-10.2011 摘要:Morin-Brureau M, Lebrun A, Rousset M-, Fagni L, Bockaert J, de Bock F, Lerner-Natoli M. Epileptiform Activity Induces Vascular Remodeling and Zonula Occludens 1 Downregulation in Organotypic Hippocampal Cultures: Role of VEGF Signaling Pathways. Journal of Neuroscience. 2011 Jul 20;31(29):10677–88. doi: 10.1523/jneurosci.5692-10.2011.