CAS: 345-92-6; Bis(4-Fluorophenyl)Methanone

上下游产品

tetrachloromethane fluorobenzene phosgene dichloro-bis-(4-fluoro-phenyl)-methane1,1,2,2-tetrakis-(4-fluorophenyl)-ethane-1,2-diol ethyl 3,3-bis(4-fluorophenyl)-3-hydroxypropanoate 1,1-bis-(4-fluoro-phenyl)-ethanol tris-(4-fluoro-phenyl)-ethene

对氟甲苯置于aluminum (Iii) Chloride,Iron(Iii) Chloride,三乙醇胺,氯,过氧化苯甲酰体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 11.58H,反应生成 4,4'-二氟二苯甲酮
参考文献:氟苯合成4,4'-二氟二苯甲酮的制备方法及其反应装置
标题:氟苯合成4,4'-二氟二苯甲酮的制备方法及其反应装置
摘要:本发明公开了氟苯合成4,4'‑二氟二苯甲酮的制备方法及其反应装置,以对氟甲苯为原料,先通过光氯化反应合成对氟三氯甲苯,再经水解合成对氟苯甲酰氯,最终由酰基化反应制得4,4'‑二氟二苯甲酮,产物的收率达到90%以上,纯度达到99%以上,制备的过程简单,易于操作与控制,在提高产物质量同时显著降低制备成本.光氯化反应在反应装置中进行,其进料组件具有称重与推料功能,无需配备其他称重设备,防止外部称重后物料因搬运产生损耗,提高物料投加的准确性,进一步提升产物收率.反应装置的进气组件实现氯气由底部通入,并在反应液中由下而上运动,与反应液充分接触,从而增加了分子之间的碰撞几率,进一步提升产物的收率.

专利信息

专利号:US-10731001-B2
优先权日:2018-11-09
标 题 :Method for the recovery of compounds deriving from the synthesis of poly aryl ether ketone polymers
发明人：SCHON STEVEN GABRIEL; GODDARD ANDREW RICHARD; JOUANNEAU JULIEN
权利人:ARKEMA FRANCE
摘要:A method for treating a shear-thinning residue composition deriving from the synthesis of an aryl ether ketone, the residue composition including a liquid fraction and solid residues, the method including the steps of: passing said shear-thinning residue composition through a shear-generating evaporating device, between a rotating part and a stationary part; and recovering a condensed liquid fraction and separately recover concentrated solid residues.

专利号:US-6262251-B1
优先权日:1995-10-19
标题 :Method for solution phase synthesis of oligonucleotides
发明人：PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING
权利人:PROLIGO LLC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides. The method lends itself to automation and is ideally suited for large scale manufacture of oligonucleotides with high efficiency.

专利号:US-11279668-B2
优先权日:2018-03-21
标题:Asymmetric synthesis of alpha-(diarylmethyl) alkyl amines
发明人：LELETI RAJENDER REDDY; KOTTURI SHARADSRIKAR; WAMAN YOGESH; PATEL CHIRAG; SHENOY RAJESH
权利人:PIRAMAL PHARMA LTD
摘要:The present invention relates to an improved asymmetric synthesis of alpha-(diarylmethyl) alkyl amines (hereafter referred to as the compound (1)) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective lithiation of alpha-diarylmethanes. followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of chiral alpha-(diarylmethyl) alkyl amines 4 and chiral amine 5; which on subsequently removing the sulfinyl group provides corresponding alpha-(diarylmethyl) alkyl amines (1) or relative chiral amines (1″).

专利号:US-5874532-A
优先权日:1997-01-08
标 题 :Method for solution phase synthesis of oligonucleotides and peptides
发明人：PIEKEN WOLFGANG; GOLD LARRY
权利人:NEXSTAR PHARMACEUTICALS INC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides and peptides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:US-6001966-A
优先权日:1995-10-19
标题 :Method for solution phase synthesis of oligonucleotides and peptides
发明人：PIEKEN WOLFGANG; GOLD LARRY
权利人:PROLIGO LLC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides and peptides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:US-11008273-B2
优先权日:2019-02-15
标题 :Process for the manufacture of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof
发明人：ZHOU CHANGYUE; DU HONGJUN; WU WENTING
权利人:FUJIAN YONGJING TECH CO LTD
摘要:The invention relates to a new process for the manufacture or synthesis, respectively, of fluorinated benzenes and fluorinated benzophenones, and derivatives thereof, in particular of fluorobenzenes and derivatives thereof. The present invention particularly pertains to a novel environmentally friendly process for the synthesis of fluorinated benzenes and benzophenones as raw materials for the manufacture of polyaryletherketones (PAEKs).