CAS: 170848-34-7; (S)-Methyl 2-((Tert-Butoxycarbonyl)Amino)-3-Iodopropanoate

上下游产品

methyl (2S)-2-[N-(t-butoxycarbonyl)amino]-3-(4-methylbenzenesulfonyl)-oxypropionate (S)-2-tert-butoxycarbonylamino-3-methanesulfonyloxypropionic acid methyl ester N-tert-butyloxycarbonyl-L-serine methyl ester (S)-N-(tert-butoxycarbonyl)serinemethyl 2-[(tert-butoxycarbonyl)amino]acrylate (S)-methyl 2-(((tert-butoxy)carbonyl)amino)butanoate methyl N-{[(1,1-dimethylethyl)oxy]carbonyl}-L-norvalinate D-N-B°C-nor-leucine methyl ester

📜Boc-L-丝氨酸甲酯置于咪唑,碘,三苯基膦体系中,用 二氯甲烷 用作溶剂,化学反应 2.5H,以84%的收率获得boc-3-碘-D-丙氨酸甲酯
参考文献:Synthesis Of Disulfides And Diselenides By Copper-Catalyzed Coupling Reactions In Water
标题:Synthesis Of Disulfides And Diselenides By Copper-Catalyzed Coupling Reactions In Water
摘要:开发了一种简单高效的铜催化偶联反应方案,用于实现芳基卤化物与硫或硒元素之间的反应.多种二硫化物和二硒化物可以在中等至优异的收率下获得,最高可达96%.
Doi:10.1039/c3Ob40464A

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-7598403-B2
优先权日:2003-05-16
标 题 :Synthesis of chromanones
发明人：SALVATORE BRIAN A; SOLIS FERDINAND C
权利人:UNIV SOUTH CAROLINA RES FOUND
摘要:Processes for the preparation of biologically active chromanones are disclosed, including processes for the preparation of intermediates useful in the preparation of the biologically active chromanones. The chromanones and the intermediates disclosed herein may be useful for a variety of therapies, including the treatment of various cancers and the treatment of inflammation and inflammation related disorders.

专利号:US-8993762-B2
优先权日:2013-03-15
标题 :Total synthesis of thaxtomin A analogues and their intermediates
发明人：HUANG HUAZHANG; YAN DONG; XUE ZHIJIE; ZHANG HONGBO
权利人:MARRONE BIO INNOVATIONS INC; MARRONE BIO INNOVATIONS INC
摘要:Improved synthetic methods for the production of thaxtomin analogs, particularly thaxtomin A, and intermediates therefore such as substituted tryptophans and in particular, 4-nitro-L-tryptophan, and substituted phenyl acrylic acids are disclosed. Bioassays show that the synthetic thaxtomin A is not significantly different from the natural one in herbicidal activity.

专利号:US-2007203214-A1
优先权日:2003-05-16
标 题 :Synthesis Of Chromanones

专利号:US-2014275541-A1
优先权日:2013-03-15
标 题 :Total synthesis of thaxtomin a analogues and their intermediates

专利号:CN-119306709-A
优先权日:2023-07-13
标题:Synthesis method of compound containing oxo-pyrido alicyclic heterocycle or alicyclic structure and novel intermediate