CAS: 140-18-1; Benzyl 2-Chloroacetate

相似化合物

5437-45-6 140-11-4 17229-17-3

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CAS号79-11-8 氯乙酸 | CAS号100-51-6 苯甲醇 | CAS号104-15-4 对甲苯磺酸 | CAS号7757-82-6 元明粉 | CAS号79-04-9 氯乙酰氯 | CAS号53772-44-4 diphenyl-phenyl... | CAS号100-46-9 苄胺 | CAS号96-34-4 氯乙酸甲酯 | CAS号52267-51-3 Benzyl diazoacetate | CAS号7335-39-9 2-chloro-N-phen... | CAS号57443-18-2 二甲基膦酸乙酸苄酯 | CAS号140-11-4 乙酸苄酯 | CAS号30379-54-5 2-(苄氧基)乙酸苄酯 | CAS号3032-14-2 trimethyl-(2-ox... | CAS号103-41-3 肉桂酸苄酯 | CAS号79-11-8 氯乙酸 | CAS号4453-79-6 2-benzyl-1,3,5-... | CAS号100499-89-6 醋氯芬酸苄酯 | CAS号15097-38-8 (苄氧羰基亚甲基)三苯基膦 | CAS号7396-44-3 二乙基膦酰基乙酸苄酯

碘乙酸苄基酯置于1,10-菲罗啉,Iron(II) Chloride体系中,用 乙腈 用作溶剂,化学反应 0.5H,以85%的收率获得氯乙酸苄酯
参考文献:Fecl2介导的菲咯啉配体加速碘代烷的亲核氯化
标题:Fecl2介导的菲咯啉配体加速碘代烷的亲核氯化
摘要:Alkyl Halides Have Been Considered Not Only Important Building Blocks But Also Useful Intermediates In Synthetic Methods Of Nucleophilic Substitution,Metal-Halogen Exchange,And Cross-Coupling Reactions. As The Practical Synthesis Of Various Alkyl Halides,The Halogen Exchange Is One Of The Fundamental And Efficient Reactions,Which Is Mainly Used For Preparing Alkyl Bromides Or Iodides. Finkelstein-Type Reactions(1) Have Been Well Studied For The Conversion Of Alkyl Chlorides To The Corresponding Bromides Or Iodides And Alkyl Bromides To Iodides,Which Reaction Is An Equilibrium Shifted By Taking Advantage Of The Different Solubility Of The Resulting Sodium Salt In Acetone. However,The Reverse Processes,The Replacement Of Iodide By Bromide Or Chloride,Or Of Bromide By Chloride,Were Not Simple.
Doi:10.1002/bkcs.11453

专利信息

专利号:US-2010022541-A1
优先权日:2006-09-25
标题:Chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors
发明人：ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
权利人:ESCAICH SONIA; DENIS ALEXIS; MOREAU FRANCOIS; GERUSZ VINCENT; DESROY NICOLAS
摘要:The invention relates to new compounds having heptose synthesis inhibitory properties, of formula (I) or a pharmaceutically acceptable salt, or prodrug thereof, wherein A is an aryl or heterocycle, optionally substituted by one or several identical or different R such as H, C1-C10 alkyl, C1-C10 alkyl-OR 1 , C1-C10 alkyl-NR 1 R 1 , alkoxy, hydroxy, thioalkyl, aryl, heterocycle, halogen, nitro, cyano, CO 2 R 1 , NR 1 R 1 , NR 1 C(O)R 1 , C(O)NR 1 R 1 , NR 1 C(S)R 1 , C(S)NR 1 R 1 , SO 2 NR 1 R 1 , SO 2 R 1 , NR 1 SO 2 R 1 , NR 1 C(O)NR 1 R 1 , NR 1 C(O)OR 1 , NR 1 C(S)NR 1 R 1 , NR 1 C(S)OR 1 , R 1 Câ•?NOR 1 , C(O)R 1 , aryloxy, thioaryl, alkenyl, alkynyl R1 identical or different is H or C1-C10 alkyl B 1 , B 2 , B 3 identical or not represent C, N, O, S to form a five-membered aromatic ring wherein from one to three carbon atoms are replaced by a heteroatom selected from S, O, N optionally substituted by one or several identical or different R such as defined above B 4 is C or N Y is H, C1-C10 alkyl, alkoxy, thio-alkyl, optionally substituted by one or several identical or different R such as defined above W is C, O or N, substituted or not by one or several C1-C10 alkyl radicals D is an heterocycle optionally substituted by one or several identical or different R such as defined aboe.

专利号:US-9174924-B2
优先权日:2007-09-17
标 题 :Hydrolysable linkers and cross-linkers for absorbable polymers
发明人：BEZWADA RAO S
权利人:BEZWADA BIOMEDICAL LLC
摘要:The present invention relates to the discovery of new class of linear and multiarmed hydrolysable linkers and cross linkers for use in the synthesis of biodegradable polymers such as, polyesters, polyurethanes, polyamides, polyureas and degradable epoxy amine resin. The linear and multiarmed hydrolysable linkers of the present invention include symmetrical and/or unsymmetrical ether carboxylic acids, amines, amide diols, amine polyols and isocyanates.

专利号:US-7189749-B2
优先权日:1999-06-25
标 题 :Substituted phenoxyacetic acids
发明人：VAN ZANDT MICHAEL C
权利人:INST FOR PHARM DISCOVERY INC
摘要:Disclosed are substituted phenoxyacetic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds, alone or in combination with other therapeutic agents, and methods of treatment employing the compounds and pharmaceutical compositions, as well as methods for their synthesis.

专利号:AU-2007301607-A1
优先权日:2006-09-25
标 题 :Substituted heterocyclylcarbonylamino-acetic-acid-derivatives as inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors

专利号:CA-2664342-A1
优先权日:2006-09-25
标题:New chemical inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors

专利号:EP-2104671-A2
优先权日:2006-09-25
标题:Substituted heterocyclylcarbonylamino-acetic-acid-derivatives as inhibitors of bacterial heptose synthesis, methods for their preparation and biological applications of said inhibitors