CAS: 115549-05-8; 2,3,4-Trichloro-5-Fluorobenzoyl Chloride

该化合物是一种卤代芳烃氯化物,在有机合成方面有很大用途.其结构包括多种氯替代物和氟原子,增强了其作为制药,农用化学品和特殊化学品制作中间体的回活动性.卤素组的电提取效应促进了核生殖替代反应,使其对构建复杂的分子框架很有价值.在受控条件下,化合物的高度纯度和稳定性确保了合成应用的一贯性.其形成氨化物,酯类和其他衍生物的多功能凸显了其在精细化学制造中的重要性.由于其湿度敏感度和潜在腐蚀性,需要妥善处理.

结构式图片

上下游产品

5-氟-2,3,4-三氯苯甲酸 2,3,4-Trichloro-5-Fluorobenzoic Acid 115549-04-7

合成工艺路线路线简述

    📜5-氟-2,3,4-三氯苯甲酸置于氯化亚砜体系中,化学反应生成2,3,4-三氯-5-氟苯甲酸
    参考文献:Process For The Preparation Of Benzoic Acid Derivatives
    标题:Process For The Preparation Of Benzoic Acid Derivatives
    摘要:一种制备式子为##str1##的化合物的方法,其中x.Sup.1和x.Sup.2分别独立地为氯或氟,而y为氯,溴,氟或碘,包括将式子为##str2##的化合物经过sandmeyer或balz-Schiemann反应以产生式子为##str3##的羧酸,然后将羧酸(Ia)转化为式子为##str4##的酰氯.化合物(II)是新的,该产品是抗菌剂的已知中间体.

    海关参考信息

    专利信息


    专利号:US-5792892-A
    优先权日:1994-04-28
    标 题:Processes for preparing aromatic, bromine-containing compounds, novel bromine-containing compounds, and their use as intermediate products in the synthesis of active agents
    发明人:HAGEMANN HERMANN
    权利人:BAYER AG
    摘要:The present invention relates to processes for the preparation of bromine-containing aromatic compounds, to novel bromine-containing compounds and to their use as intermediates in the synthesis of active substances. Processes according to the invention for the preparation of known and novel bromine-containing compounds are characterized by specific conditions.

    专利号:JP-H09512540-A
    优先权日:1994-04-28
    标题 :Process for the production of bromine-containing aromatic compounds, novel bromine-containing compounds and their use as intermediates for the synthesis of active substances

    专利号:US-11059788-B2
    优先权日:2017-06-12
    标 题:Streamlined syntheses of fluoroquinolones
    发明人:GUPTON FRANK B; TOSSO PERRER N
    权利人:UNIV VIRGINIA COMMONWEALTH
    摘要:Methods of synthesizing fluoroquinolones such as ciprofloxacin are provided. The methods utilize affordable materials, reduce the number of synthesis steps and provide high yields.

    专利号:EP-0757667-B1
    优先权日:1994-04-28
    标 题:Processes for preparing aromatic, bromine-containing compounds, novel bromine-containing compounds, and their use as intermediate products in the synthesis of active agents

    专利号:DE-4414841-A1
    优先权日:1994-04-28
    标 题:Aromatic compounds containing bromine, processes for their preparation and their use as intermediates in the synthesis of active substances

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