CAS: 607-67-0; 4-Hydroxy-2-Methylquinoline

该化合物是奎诺林家族的有机化合物,其特征为:基质结构中附带一个氢氧化物组(-OH)和一个甲基组(-CH3),该组由一个有引信的苯乙烯和环组成;该化合物的特点是其青黄色至褐色色色的颜色,在室温中呈现一种坚固状态;已知其在各个领域的潜在应用,包括药物,可以作为其他化合物合成的中间体;氢氧基体组的存在有助于其再活动,允许氢结合并影响极地溶剂中的溶解性;此外,4-氢氧-2-甲基基线可能展示生物活动,使其对医药化学感兴趣;但与许多有机化合物一样,它应当谨慎处理,考虑到潜在的毒性和环境影响;在实验室环境中与该物质合作时,应当注意适当的安全措施.

结构式图片

相似化合物

165112-03-8 15644-82-3 15644-90-3

物理性质

MSDS等安全信息

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

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合成工艺路线路线简述

    📜2,3-二氢-2-甲基-4(1H)-喹啉酮置于potassium Carbonate,钯,顺丁烯二酸体系中,化学反应生成 4-羟基-2-甲基喹啉
    参考文献:Preparation Of 4-Hydroxyquinoline Compounds
    标题:Preparation Of 4-Hydroxyquinoline Compounds

    海关参考信息

    专利信息


    专利号:US-2024002348-A1
    优先权日:2020-08-22
    标 题:Quinolone compounds and process for preparation thereof
    发明人：PABBARAJA SRIHARI; MEHTA GOVERDHAN; SINGH SHWETA
    权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN
    摘要:The present invention relates to quinolones of formula (I) and process for its preparation by amine insertion into aryl-ynones thereof. [Formula I] The invention further relates to the process to obtain the natural products such as: graveoline, graveolinine, pseudane IV, pseudane VII, pseudane VIII and pseudane XII. The invention also describes the process for the total synthesis of waltherione F in concise approach from the quinolone synthesized. [Formula II]

    专利号:US-2007060558-A1
    优先权日:2004-07-30
    标 题 :Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents
    发明人：SANCHEZ MURIEL; MEUNIER BERNARD
    权利人:CENTRE NAT RECH SCIENT
    摘要:The invention concerns an aminoquinoline-antibiotic hybrid compound of general formula (I): Q—(Y 1 ) p —(U) p —(Y 2 ) p -A: wherein Q represents an aminoquinoline, (Y 1 ) p (U) p —(Y 2 ) p″ is an optional spacer and A is an antibiotic residue. The invention enables the antibiotic residue activity to be unexpectedly enhanced.

    专利号:US-2021313517-A1
    优先权日:2012-01-20
    标题:Synthesis of aza-acenes as novel n-type materials for organic electronics

    专利号:CN-116377457-A
    优先权日:2023-03-04
    标 题:A kind of electrochemical synthesis method of haloquinolin-4(1H)-one derivative

    专利号:RU-2733750-C2
    优先权日:2015-09-02
    标题:Derivatives of carboxy-substituted (hetero)aromatic rings, method of synthesis and use thereof

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    主要参考文献

    [参考文献]: Bin Yang, Et Al. Prediction Of Setschenow Constants Of N-Heteroaromatics In Nacl Solutions Based On The Partial Charge On The Heterocyclic Nitrogen Atom. Environ Sci Pollut Res Int. 2016 Feb;23(4):3399-405.

    合成参考文献


    摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 361.
    摘要:Ruan, Z.; Huang, Z.; Kuciński, K.; Ackermann, L., Science of Synthesis: Special Topics, (2021) 1, 208.
    摘要:Sharma, U.; Parmar, D.; Sumit; Manisha, Science of Synthesis: Knowledge Updates, (2024) 2, 113.
    摘要:Zhang, C.; Duan, Y.-N., Science of Synthesis: Hypervalent Halogens in Organic Synthesis, (2025) .
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