专利号:US-2023399302-A1 优先权日:2020-10-29 标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds 发明人:LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS 权利人:H LEE MOFFITT CANCER CT & RES 摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.
专利号:US-9334174-B2 优先权日:2011-10-26 标题 :Method for synthesizing spherical porous titanium oxide nanoparticles, spherical porous titanium oxide nanoparticles produced by said synthesis method, and carrier for gene gun which comprises said spherical porous titanium oxide nanoparticles 发明人:KOBIRO KAZUYA; WANG PENGYU; OHAMA TAKESHI 权利人:KOBIRO KAZUYA; WANG PENGYU; OHAMA TAKESHI; UNIV KOCHI TECHNOLOGY 摘要:Problem. Provided are a method for synthesizing spherical porous titanium oxide nanoparticles, which is easy to operate, does not take a long time for synthesis, and can easily adjust the particle diameter and the pore diameter of the spherical porous titanium oxide nanoparticles in accordance with the application thereof; spherical porous titanium oxide nanoparticles produced by the synthesizing method; and a gene gun carrier consisting of the spherical porous titanium oxide nanoparticles. Solution. A method for synthesizing spherical porous titanium oxide nanoparticles, includes: a step of reacting titanium isopropoxide and carboxylic acid in supercritical fluid, wherein the supercritical fluid is supercritical methanol, and the carboxylic acid is formic acid, acetic acid, benzoic acid, o-phthalic acid, fumaric acid, or maleic acid.
专利号:WO-2023114200-A2 优先权日:2021-12-14 标题 :Methods for the synthesis of complement factor d inhibitors and intermediates thereof
专利号:US-8329686-B2 优先权日:2006-08-29 标题:Isatin analogues and uses therefor 发明人:MACH ROBERT H; WELCH MICHAEL; CHU WENHUA; ROTHFUSS JUSTIN 权利人:MACH ROBERT H; WELCH MICHAEL; CHU WENHUA; ROTHFUSS JUSTIN; UNIV WASHINGTON 摘要:Novel isatin analogues, including isatin analogues comprising Michael Acceptors (IMAs) are disclosed. Further disclosed are methods of synthesis of the isatin analogues, and uses of the analogues, including inhibition of caspase-3 and caspase-7, and in vivo imaging of apoptosis by Positron emission tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
专利号:EP-4551564-A2 优先权日:2022-07-05 标 题:One-step synthesis of beta-alkylidene-gamma-lactones
专利号:WO-2023114198-A2 优先权日:2021-12-15 标题 :Methods for the synthesis of complement factor d inhibitors