CAS: 327056-73-5; 3-Chloro-5-Fluorobenzonitrile

上下游产品

CAS号33863-76-2 1-溴-3-氯-5-氟苯 | CAS号557-21-1 氰化锌 | CAS号304853-30-3 3-(4,4-二甲基-2-氧代... | CAS号920036-41-5 3-chloro-5-(2-c...

1-溴-3-氯-5-氟苯,氰化锌置于(1,1'-Bis(Diphenylphosphino)Ferrocene)Palladium(II) Dichloride 锌体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 0.91H,以66%的收率获得3-氯-5-氟苯腈
参考文献:Wo2006/67587
标题:Wo2006/67587

专利信息

专利号:US-9550757-B2
优先权日:2010-03-05
标题:Nuclear transport modulators and uses thereof
发明人：SHACHAM SHARON; KAUFFMAN MICHAEL; SANDANAYAKA VINCENT P; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to the field of nuclear transport modulators, e.g., CRM1 inhibitors, and more particularly to new substituted-heterocyclic azole compounds, the synthesis and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with CRM1 activity such as in treating cancer and other neoplastic disorders, inflammatory diseases, disorders of abnormal tissue growth and fibrosis including cardiomyopathy, pulmonary fibrosis, hepatic fibrosis, glomerulonephritis, and other renal disorders, and for the treatment of viral infections (both acute and chronic).

专利号:US-5098466-A
优先权日:1985-08-20
标 题 :Compounds
发明人：ANDERSON RICHARD J; LEIPPE MICHAEL M; BAMBERG JOE T
权利人:SANDOZ LTD
摘要:Substituted semicarbazones, thiosemicarbazones and isothiosemicarbazones and salts thereof, intermediates therefor, synthesis thereof, and the use of said compounds for the control of weeds.