CAS: 273-13-2; 2,1,3-Benzothiadiazole

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CAS号95-54-5 邻苯二胺(OPD) | CAS号480-96-6 苯并氧化呋咱 | CAS号4377-90-6 1,3-Dihydro-2,1... | CAS号2958-89-6 4-Morpholinesul... | CAS号15995-56-9 1,2-bis(sulfiny... | CAS号14208-17-4 3,5-Cyclohexadi... | CAS号1753-97-5 triphenyl-[2-[(... | CAS号39145-59-0 benzene-o-diami... | CAS号3529-57-5 2,1,3-苯并噻二唑-4-甲酸 | CAS号5170-68-3 2,1,3-苯并硫杂二唑-4-甲醛 | CAS号2207-28-5 4-氯苯[c][1,2,5]并噻二唑 | CAS号352018-95-2 4-碘-2,1,3-苯并噻二唑 | CAS号95-54-5 邻苯二胺(OPD) | CAS号874-37-3 2,1,3-苯并噻唑-5-胺 | CAS号73713-79-8 2,1,3-苯并噻二唑-4-磺酰氯 | CAS号63224-42-0 4,7-二溴-2,1,3-苯并硒二唑 | CAS号767-64-6 4-氨基-2,1,3-苯并噻二唑 | CAS号534-85-0 N-苯基邻苯二胺

邻苯二胺置于氯化亚砜,三乙胺体系中,用 二氯甲烷 用作溶剂,化学反应 4.0H,以93%的收率获得2,1,3-苯并噻二唑
参考文献:π扩展分子2,1,3-苯并噻二唑的光物理和电化学性质
标题:π扩展分子2,1,3-苯并噻二唑的光物理和电化学性质
摘要:4,7-二溴-2,1,3-苯并噻二唑与芳基硼酸(苯基,1-萘基,4-甲氧基苯基,4-氯苯基和4-三氟甲基苯基)在催化量的ncp-夹钳式金枪鱼环的存在下反应能够以高收率获得光致发光的π扩展4,7-二芳基-2,1,3-苯并噻二唑4A-E.这些4,7-二芳基-2,1,3-苯并噻二唑具有高荧光量子产率,高电子亲和力和足够的带隙值,可作为oled进行测试.由于存在两种阻转异构体,因此4,7-双萘-2,1,3-苯并噻二唑4B具有两个不同的寿命(双指数衰减).4,7-二乙炔基-2,1,3-苯并噻二唑6的sonogashira偶联反应与相应的卤代芳基化合物(碘代苯,1-溴代萘,4-碘代苯甲醚,4-溴代n,N-二甲基苯胺和2-溴代吡啶)提供光致发光的π扩展的4,7-双-炔基芳基-2,1,3-苯并噻二唑7A-E,也高产.这些4,7-二乙炔基-2,1,3-苯并噻二唑也具有较高的荧光量子产率,较高的电子
Doi:10.1016/j.Tet.2005.08.093

专利信息

专利号:US-11161827-B2
优先权日:2019-04-05
标 题 :Catalytic systems for stereoselective synthesis of chiral amines by enantiodivergent radical C—H amination
发明人：Zhang xiao-xiang; Lang kai
权利人:TRUSTEES BOSTON COLLEGE; THE TRUSTEES OF BOSTON COLLEGE
摘要:In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp 3 )—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-11186678-B2
优先权日:2018-11-30
标 题 :Radical cascade-enabled synthesis of precision polymers with complex main-chain structures
发明人：NIU JIA; HUANG HANCHU; WANG WENQI
权利人:TRUSTEES BOSTON COLLEGE
摘要:Radical cascade reactions enabling sequence-controlled ring-closing polymerization and ring-opening polymerization for the controlled synthesis of polymers with complex main-chain structures are provided. Facile syntheses leading to low-strain macrocyclic monomers consisting of the ring-opening triggers and extended main-chain structures are also provided. The present disclosure further provides methods for excellent control over polymer molecular weights and molecular weight distributions and high chain-end fidelity allows for the preparation of polymeric systems with well-defined architectures. Further provided are the general nature of the radical cascade-triggered transformations in polymer chemistry, and its application to the synthesis of polymers with diverse main-chain structural motifs with tailored functions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

专利号:US-11912647-B2
优先权日:2020-05-22
标 题:Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation
发明人：CRICH DAVID; HETTIKANKANAMALAGE ASIRI; HILL JARVIS
权利人:UNIV GEORGIA
摘要:In one aspect, the disclosure relates to a method for the direct synthesis of complex N,N,O-trisubstituted hydroxylamines by N—O bond formation. In another aspect, the method can successfully be employed using a wide variety of commercially available alcohols and secondary amines and enables the construction of large fragment-based libraries of trisubstituted hydroxylamines for drug discovery purposes. Also disclosed are N,N,O-trisubstituted hydroxylamines having low basicity, high stability at ambient temperatures, and an inherent lack of reactivity towards acetylating and sulfonylating enzymes that confer mutagenicity on less-substituted hydroxylamines.

专利号:US-2024083829-A1
优先权日:2020-12-31
标 题:Process for the asymmetric synthesis of isopiperitenol
发明人：LIST BENJAMIN; GRIMM JOYCE; ZHOU HUI; LIU LUPING; ZWERSCHKE ALEXANDER
权利人:STUDIENGESELLSCHAFT KOHLE GGMBH
摘要:The present invention refers to a process for the asymmetric synthesis of isopiperitenol and successor compounds.

专利号:US-9273023-B2
优先权日:2011-11-01
标 题:Modular synthesis of graphene nanoribbons and graphene substructures from oligo-alkynes
发明人：ALABUGIN IGOR; BYERS PHILIP M
权利人:UNIV FLORIDA STATE RES FOUND
摘要:A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.

专利号:US-2004101523-A1
优先权日:1989-07-27
标题:Renal-selective prodrugs for control of renal smpathetic nerve activity in the treatment of hypertension
发明人：REITZ DAVID B; KOEPKE JOHN P; BLAINE EDWARD H; SCHUH JOSEPH R; MANNING ROBERT E; SMITS GLENN J
权利人:SEARLE & CO
摘要:Renal-selective prodrugs are described which are preferentially converted in the kidney to compounds capable of inhibiting synthesis of catecholamine-type neurotransmitters involved in renal sympathetic nerve activity. The prodrugs described herein are derived from inhibitor compounds capable of inhibiting one or more of the enzymes involved in catecholamine synthesis, such compounds being classifiable as tyrosine hydroxylase inhibitors, or as dopa-decarboxylase inhibitors, or as dopamine-β-hydroxylase inhibitors. These inhibitor compounds are linked to a chemical moiety, such as a glutamic acid derivative, by a cleavable bond which is recognized selectively by enzymes located predominantly in the kidney. The liberated inhibitor compound is then available in the kidney to inhibit one or more of the enzymes involved in catecholamine synthesis. Inhibition of renal catecholamine synthesis can suppress heightened renal nerve activity associated with sodium-retention related disorders such as hypertension. Conjugates of particular interest are glutamyl derivatives of dopamine-β-hydroxylase inhibitors, of which N-acetyl-γ-glutamyl fusaric acid hydrazide (shown below) is preferred.