CAS: 1493-27-2; 1-Fluoro-2-Nitrobenzene

相似化合物

19064-24-5 446-35-5 364-74-9

上下游产品

fluorobenzene nitro acetate 4-Fluoro-3-nitroaniline 2-Chloronitrobenzene N-cyclohexyl-2-nitroaniline (2-nitrophenyl)-p-tolylamine 2-nitro-4'-methoxydiphenylamine N-Ethyl-2-nitroaniline

1,2-二硝基苯置于四丁基氟化铵体系中,用 四氢呋喃 用作溶剂,化学反应 1.5H,以97.4%的收率获得1-氟-2-硝基苯
参考文献:使用四丁基氟化铵作氟化剂的温和有效的亲核芳族氟化方法
标题:使用四丁基氟化铵作氟化剂的温和有效的亲核芳族氟化方法
摘要:摘要已发现无水四丁基氟化铵(tbafanh.)是一种高效的氟化试剂,用于亲核芳香族氟化反应,例如氟脱氮或卤素交换(halex)反应.在出乎意料的温和的反应条件下以高至优异的收率形成产物,并且在这些反应中未检测到苯酚或醚副产物.
Doi:10.1016/j.Cclet.2009.10.014

专利信息

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:WO-2025101716-A1
优先权日:2023-11-07
标题:Processes for synthesis of trifunctionalized sulfur(vi) compounds
发明人：LOPCHUK JUSTIN; SHULTZ ZACHARY; ATHAWALE PARESH
权利人:H LEE MOFFITT CANCER CT & RES
摘要:This disclosure describes processes for the asymmetric synthesis of trifunctionalized sulfur(VI) containing organic compounds of Formula I and Formula VI, as well as compounds of Formula I and Formula VI prepared by the processes described.

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-9233989-B2
优先权日:2011-10-11
标题:Sila analogs of oxazolidinone derivatives and synthesis thereof
发明人：REDDY DUMBALA SRINIVASA; BALAMKUNDU SEETHARAM SINGH; RAMESH REMYA
权利人:COUNCIL SCIENT IND RES
摘要:The invention discloses silaanalogs of oxazolidinone compounds, to pharmaceutical compositions and to the synthesis of the oxazolidinone derivatives of formula I. The invention further relates to methods of treating a subject suffering with gram positive pathogens including those resistant to methicillin and vancomycin using the compound(s) or modulation of coagulation properties of blood-clotting cascade or compositions of the oxazolidinone derivatives of the invention.

专利号:US-11691135-B2
优先权日:2020-10-15
标 题:Synthesis of alkynones via carbonylative Sonogashira coupling reactions catalyzed by Pd(II)-N-Heterocyclic carbene-pyridine complexes
发明人：EL ALI BASSAM; MANSOUR WASEEM; FETTOUHI MOHAMMED
权利人:UNIV KING FAHD PET & MINERALS; SAUDI ARABIAN OIL CO
摘要:This disclosure relates to N-substituted Pd(II)-N-heterocyclic carbene-pyridine complexes, methods of preparing the complexes, and methods of using the complexes in Sonogashira coupling reactions.

专利号:US-6229055-B1
优先权日:1996-04-12
标题 :Synthesis of fluorinated xanthene derivatives
发明人：KLAUBERT DIETER H; GEE KYLE R
权利人:MOLECULAR PROBES INC
摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.