CAS: 134-05-4; 2-(4-(((2-Amino-4-Oxo-3,4-Dihydropteridin-6-yl)Methyl)Amino)Benzamido)-4-Formylpentanedioic Acid

上下游产品

formic acid folate folinic acid (6RS)-5,10-diformyl-5,6,7,8-tetrahydrofolic acid

专利信息

专利号:EP-1645276-A1
优先权日:2004-10-08
标题:Treatment of neurodegenerative disorders
发明人：DURGA JANE; VERHOEF PETRA
权利人:WAGENINGEN CT FOR FOOD SCIENCE
摘要:The present invention is dedicated to the treatment of neurodegenerative disorders, in particular age related cognitive decline and age related hearing loss. These disorders can be alleviated by increasing 10-formyltetrahydrofolate or increasing thymidylate synthesis. The invention is of particular benefit to subjects that are MTHFR 677CT heterozygote and MTHFR 677CC homozygote. n The substance that increases 10-formyltetrahydrofolate or increases thymidylate synthesis is selected from 10-formyltetrahydrofolate, 5-formyltetrahydrofolate, 5,10-methenyltetrahydrofolate, 5,10-methylentetrahydrofolate, methionine, S-adenosylmethionine and poly-glutamate forms of 10-formyltetrahydrofolate, 5-formyltetrahydrofolate, 5,10-methenyltetrahydrofolate and 5,10-methylentetrahydrofolate and the substance may be in an acid or salt or ester form.

专利号:WO-2021237410-A1
优先权日:2020-05-25
标 题:Co-production method for multiprotein system, co-production system for multiprotein system and use thereof
发明人：DAI ZHUOJUN; LI PENGCHENG; ZHANG XI
权利人:SHENZHEN INST ADV TECH
摘要:Provided are a co-production method for a multiprotein system, a co-production system for a multiprotein system and use thereof. Specifically, a vector for expressing a bacteriolytic protein and a plurality of vectors for expressing proteins are co-transferred into a protein expression strain, so that the obtained co-expression strain expresses corresponding proteins and bacteriolytic protein. As growth of the co-expression strain, the generated bacteriolytic protein acts on the co-expression strain, so that the co-expression strain is subject to autonomous lysis, and the expressed proteins are released, thereby forming a multi-protein system which can be used for in vitro synthesis of proteins and/or compounds.

专利号:US-7118883-B2
优先权日:2000-12-28
标 题:Process for producing peptides by using in vitro transcription/translation system
发明人：INOUE AKIO; SHIMIZU YOSHIHIRO; UEDA TAKUYA
权利人:POST GENOME INST CO LTD
摘要:The present invention relates to a reaction system whereby a peptide produced in an in vitro peptide synthesis system can be efficiently isolated at a high purity from the reaction system. Thus the present invention is a process for producing a peptide or a peptide derivative by using a reaction system of transcribing a DNA into an RNA and then translating the RNA produced or a reaction system of translating an RNA in vitro wherein at least one protein component of the reaction system is labeled with a first substance which adheres to a second substance, and said second substance is used as an adsorbent for capturing said labeled protein components after translating.