专利号:US-12180228-B2 优先权日:2019-06-05 标题:Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof 发明人:MOVASSAGHI MOHAMMAD; OLSSON CHASE ROBERT; SCOTT TONY Z; CHEAH JAIME; PAYETTE JOSHUA NATHANIEL 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:The present disclosure provides, e.g., compounds, compositions, kits, methods of synthesis, and methods of use, involving epipolythiodiketopiperazines and polythiodiketopiperazines.
专利号:WO-2025110754-A1 优先权日:2023-11-22 标题:Composition for treating wound or inhibiting skin wrinkle formation 发明人:HAHN JANG HEE; KIM MIN SEO; YOO HYO JEONG; KIM JEONG HOE 权利人:HAN DO SOOK 摘要:The present invention provides a pharmaceutical composition for wound treatment and a cosmetic composition for inhibiting skin wrinkle formation, both comprising a specific peptide. Acting as an agonist for FGFR2, the peptide effectively induces FGFR2 signal transduction as well as promoting cell proliferation and inducing the synthesis of collagen, elastin, and HAS2. The peptide can be advantageously used for wound healing and the inhibition of skin wrinkle formation.
专利号:US-2004091900-A1 优先权日:2002-06-21 标 题:Materials and methods for providing plants with increased resistance to environmental stress 发明人:GUY CHARLES L; KAPLAN FATMA; SUNG DONG YUL 摘要:The subject invention pertains to materials and methods for protecting plants and plant organelles, such as chloroplasts, during thermal (heat and cold) stress, and other forms of environmental stress such as water and salt stress. In one embodiment, a plant is transformed with a polynucleotide that encodes a protein that produces, catalyzes the synthesis of or results in the production of maltose or a maltose alcohol. In an exemplified embodiment, the polynucleotide encodes a β-amylase enzyme that is localized at the chloroplast. The subject invention also concerns plants and plant tissue transformed with a polynucleotide that encodes a protein that produces or results in the production of maltose or a maltose alcohol.
专利号:CN-104262242-B 优先权日:2014-09-22 标题 :Synthesis of 3,5-diiodo-4-aminopyridine by in situ generation of iodo reagent
专利号:CN-104262242-A 优先权日:2014-09-22 标 题:Synthesis of 3,5-diiodo-4-aminopyridine by in situ generation of iodo reagent
专利号:WO-2025110752-A1 优先权日:2023-11-22 标题 :Composition for treating wound or inhibiting skin wrinkle formation 发明人:HAHN JANG HEE; KIM MIN SEO; YOO HYO JEONG; KIM JEONG HOE 权利人:HAN DO SOOK 摘要:The present invention provides: a pharmaceutical composition for wound healing and a cosmetic composition for inhibiting skin wrinkle formation, both comprising a specific peptide. The peptide acts as an agonist for IGF-1R, thereby effectively inducing IGF-1R signal transduction, promoting cell proliferation, and inducing the synthesis of collagen, elastin, and HAS2. The peptide can be advantageously used for wound healing and the inhibition of skin wrinkle formation.