CAS: 85-34-7; Chlorfenac

该化合物是一种氯化苯氧乙酸衍生物,主要用作农业和非作物环境中的除草剂,用于在宽叶叶除草控制,其行动方式包括模仿天然植物荷尔蒙,扰乱生长模式,导致易感染植物的细胞分化不受控制.化合物显示有选择性的活动,对目标杂草有效,同时在正确应用时尽量减少对适当作物的损害.氯氟化碳展示残余土壤活动,对新出现的杂草提供广泛的控制.配方可能包括盐类或酯类,以优化溶解性和吸收.适当应用时间和遵守建议的速率对于功效和减少潜在目标外影响至关重要.

结构式图片

欧盟法规

统一分类与标签ECHA物质工作场所安全标识要求ECHA物质C&L通报REACH预注册废弃物危险特性清单

上下游产品

(2,3,6-trichlorophenyl)acetonitrile 1,2,4-trichloro-3-methylbenzene 2,3,6-trichlorobenzyl bromide3-(2,3,6-trichlorophenyl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione Tributylzinn-2,3,6-trichlorphenylacetat

合成工艺路线路线简述

    2,3,6-三氯甲苯置于过氧化苯甲酰 Sodium Hydroxide,N-溴代丁二酰亚胺(Nbs)体系中,用 四氯化碳,乙醇,二甲基亚砜 作为反应溶剂,化学反应 5.0H,反应生成 伐草克
    参考文献:作物和杂草植物中氯苯丙氨酸的代谢与潜在除草终产物的形成有关☆
    标题:作物和杂草植物中氯苯丙氨酸的代谢与潜在除草终产物的形成有关☆
    摘要:摘要 12 种合成 D,L-氯苯丙氨酸在几种作物和杂草植物中的代谢情况已被检测.25 克从灌木豆,大豆,玉米,猪草,羊羔和大狗尾草的切下枝条或叶子的样品在连续光照下代谢 10-4 M D,L-氯苯丙氨酸溶液 24 小时.然后将植物样品用 80% 甲醇提取,并将可溶性酸性代谢物分馏到乙醚中.每种醚浓缩物通过从 Prepsep C18 柱的分级洗脱进行部分纯化,然后通过 HPLC 进行分析.收集的馏分用五氟苄溴酯化并通过 Gc-Ms 检查以证明存在氯苯乙酸,氯苯甲酸和/或氯肉桂酸的 Pfb 酯.
    DOI:10.1016/0031-9422(88)80592-2

    海关参考信息

    专利信息


    专利号:WO-2024256370-A1
    优先权日:2023-06-13
    标 题 :Synthesis of glufosinate using an amidase-based process
    发明人:ZIMMERMANN GUNTHER; POTT MORITZ STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of preparing glufosinate, comprising the steps of hydrolysing an N-carbamoyl glufosinate amide with an Amidase enzyme to form an N- carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N- carbamoyl amino acid compound.

    专利号:WO-2024168196-A1
    优先权日:2023-02-08
    标 题:Systems and methods for enzymatic synthesis of polynucleotides containing non-standard nucleotide basepairs
    发明人:MARCHAND JORGE; KAWABE HINAKO
    权利人:UNIV WASHINGTON
    摘要:Systems and methods for generating defined base pairs in a sequence-defined library format that include at least one non-standard nucleotide in a base pair. Non-standard base pairs can be created using a nucleic acid polymerase ( e.g. , DNA polymerase, RNA polymerase, terminal deoxynucleotide polymerase) for blunt-end tailing addition of the non-standard base, which then can be ligated to another nucleotide end. The nucleotide sequences containing non-standard base pairs can be used to generate libraries for basecalling models of the non-standard base with next-generation sequencing (NGS) platforms and sequencing non-standard nucleotide sequences, including xenonucleotide (XNAs).

    专利号:US-2025120400-A1
    优先权日:2021-12-10
    标题:Synthesis of glufosinate using a hydantoinase-based process
    发明人:DITRICH KLAUS; BREUER MICHAEL; POTT MORITZ STEFAN; ZIMMERMANN GUNTHER; SEEMAYER STEFAN
    权利人:BASF SE
    摘要:The present invention relates to a method of manufacturing glufosinate, comprising the steps of hydrolysing a hydantoin with a Hydantoinase enzyme to form a N-carbamoyl amino acid compound followed by cleaving off the carbamoyl moiety of said N-carbamoyl amino acid compound.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:ES-2717283-T3
    优先权日:2012-07-24
    标 题:Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6- (4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and herbicides inhibitors of VLCFA synthesis and synthesis of fatty acids / lipids
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    主要参考文献


    1: Rosenberg A. 2,3,6-Trichlorophenylacetic acid (fenac) degradation in aqueous and soil systems. Bull Environ Contam Toxicol. 1984 Apr;32(4):383-90.

    合成参考文献


    摘要:Farm Chemicals Handbook., -(C135), 1991
    摘要:Chemistry of Pesticides, Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971, -(153), 1971
    摘要:Lyman WJ et al; Handbook of Chemical Property Estimation Methods NY: McGraw-Hill Chapt 5 (1982)
    摘要:Rosenberg A; Bull Environ Contam Toxicol 32: 383-90 (1987)
    摘要:Plimmer JR; Research Rev 33: 47-74 (1970)
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