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📜1,7-庚二醇置于草酰氯,三(三甲基硅基)硅烷,Chlorophyll A,四丁基氟化铵,Sodium Hydride,对甲苯磺酸,二甲基亚砜体系中,用 四氢呋喃,乙醚,二氯甲烷,二甲基亚砜,N,N-二甲基甲酰胺,Mineral Oil 作为反应溶剂,化学反应 47.5H,反应生成 2-辛氧基四氢-2H-吡喃
参考文献:红光介导的 Barton-Mccombie 反应
标题:红光介导的 Barton-Mccombie 反应
摘要:描述了红光介导的 Barton-Mccombie 反应,其中叶绿素 A 用作光催化剂,三(三甲基甲硅烷基)硅烷或 Hantzsch 酯用作氢源.那里...
DOI:10.1246/bcsj.20200087

专利信息

专利号:US-2013190399-A1
优先权日:2009-10-31
标 题:Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA)
发明人：RAMAN KRISHNA; TARWADE VINOD
权利人:RAMAN KRISHNA; TARWADE VINOD; MARTEK BIOSCIENCES CORP
摘要:The invention provides methods of synthesizing omega-3 and omega-6 very long chain polyunsaturated fatty acids (VLC-PUFAs, C28-C42:4, 5 and 6), analogs and derivatives thereof, pharmaceutical compositions containing these isolated VLC-PUFA compounds and therapeutic uses therefor.

专利号:WO-2011053892-A1
优先权日:2009-10-31
标 题:Synthesis and use of omega-3 and omega-6 very long chain polyunsaturated fatty acids (vlc-pufa)
发明人：RAMAN KRISHNA; TARWADE VINOD; SALEM NORMAN JR
权利人:MARTEK BIOSCIENCES CORP; RAMAN KRISHNA; TARWADE VINOD; SALEM NORMAN JR
摘要:The invention provides methods of synthesizing omega-3 and omega-6 very long chain polyunsaturated fatty acids (VLC- PUFAs, C28-C42:4,5 and 6), analogs and derivatives thereof, pharmaceutical compositions containing these isolated VLC-PUFA compounds and therapeutic uses therefor.