CAS: 63762-78-7; 1-Fluoro-2-Methoxy-4-Methylbenzene

上下游产品

CAS号63762-79-8 2-氟-5-甲基苯酚 | CAS号77-78-1 硫酸二甲酯 | CAS号700-38-9 5-甲基-2-硝基苯酚 | CAS号38512-82-2 5-甲基-2-硝基苯甲醚 | CAS号452-84-6 2-氟-5-甲基苯胺 | CAS号39538-68-6 2-甲氧基-4-甲基苯胺 | CAS号82846-18-2 4-氟-3-甲氧基苯甲酸 | CAS号63762-79-8 2-氟-5-甲基苯酚 | CAS号128495-45-4 4-氟-3-甲氧基苯甲醇 | CAS号128495-46-5 4-氟-3-甲氧基苯甲醛 | CAS号63762-80-1 2-氟-5-甲基-4-硝基苯酚 | CAS号63762-81-2 1-fluoro-2-meth...

📜2-甲氧基-4-甲基苯胺 反应生成 2-氟-5-甲基苯甲醚
参考文献:Synthesis And Evaluation Of The Antiovulatory Activity Of A Variety Of Melatonin Analogs
标题:Synthesis And Evaluation Of The Antiovulatory Activity Of A Variety Of Melatonin Analogs
摘要:A Series Of Melatonin Analogues Was Synthesized And Examined For Ovulation-Blocking Activity. Deviation From The 5-Methoxy Group Or Substitution Of The 1 Position Prevented Activity. Activity Was Not Particularly Sensitive To Minor Variations In The N-Acyl Group Nor Was It Significantly Altered By Methylation Of Position 2 Or The Alpha-Methylene; However,A Pronounced Enhancement Resulted From Halogenation Of The 6 Position.
DOI:10.1021/jm00187A015

专利信息

专利号:US-8106031-B2
优先权日:2006-05-02
标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
发明人：LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

专利号:US-9676721-B2
优先权日:2010-09-03
标题 :Compounds and compositions for the inhibition of NAMPT
发明人：BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:BAIR KENNETH W; BUCKMELTER ALEXANDRE J; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

专利号:US-9555039-B2
优先权日:2011-05-09
标题:Piperidine derivatives and compositions for the inhibition of nicotinamide phosphoribosyltransferase (NAMPT)
发明人：BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:BAIR KENNETH W; BAUMEISTER TIMM R; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; KUNTZ JUDITH D; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
摘要:The present invention relates to compounds and compositions for the inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below: Formula (I)

专利号:US-11020399-B2
优先权日:2011-05-04
标 题:Intermediates useful in the synthesis of compounds as modulators of protein kinases

专利号:US-9169209-B2
优先权日:2011-05-04
标题:Compounds and compositions for the inhibition of NAMPT
发明人：BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG
权利人:BAIR KENNETH W; BAUMEISTER TIMM; BUCKMELTER ALEXANDRE J; CLODFELTER KARL H; HAN BINGSONG; LIN JIAN; REYNOLDS DOMINIC J; SMITH CHASE C; WANG ZHONGGUO; ZHENG XIAOZHANG; FORMA TM LLC
摘要:The present invention relates to compounds and composition for inhibition of NAMPT, their synthesis, applications and antidotes. An illustrative compound of the invention is shown below.

专利号:US-9233981-B1
优先权日:2013-02-15
标题:Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
发明人：BRODNEY MICHAEL AARON; O'NEILL BRIAN THOMAS; BUTLER CHRISTOPHER RYAN; BECK ELIZABETH MARY
权利人:PFIZER
摘要:The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, n nwherein the variables R 1 and R 2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.