CAS: 620-95-1; 3-Benzylpyridine

该化合物是一种环环有机化合物,其特点是用苯基组替代的环,这种芳香化合物由于其多种反应性,通常用作制药和农用化学合成的中间体,其结构允许进一步发挥功能,使其在开发活性成分和特殊化学品方面具有价值. 3-苯丙烯在标准条件下具有良好稳定性,并且在许多有机溶剂中可溶解,便于其用于各种反应系统.该化合物平衡的亲脂性和富电子的丙烯酰胺在化学和催化过程中的效用,通常以高纯度液体或固体形式供应,确保合成应用的一贯性.

结构式图片

相似化合物

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欧盟法规

ECHA物质C&L通报REACH预注册

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合成工艺路线路线简述

  • 合成目标产物 3-Benzylpyridine 主要起始原料 3-Pyridyl Bromide And Benzaldehyde Tosylhydrazone
  • (文献来源)合成步骤主要原料 3-Pyridyl Bromide 和 Benzaldehyde Tosylhydrazone
📜1-苄基哌啶置于铬,Silica Gel,镍,铜,Sodium Sulfate体系中,化学反应生成 3-苄基吡啶
参考文献:Tereshko,A. B.; Tarasevich,V. A.; Kozlov,N. G.,Russian Journal Of Organic Chemistry,1994,Vol. 30,# 9.2,P. 1512
标题:Tereshko,A. B.; Tarasevich,V. A.; Kozlov,N. G.,Russian Journal Of Organic Chemistry,1994,Vol. 30,# 9.2,P. 1512

海关参考信息

专利信息


专利号:US-3919155-A
优先权日:1970-12-18
标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人:SQUIRE EDWARD NOONAN
权利人:DU PONT
摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.

专利号:US-4031106-A
优先权日:1973-12-19
标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人:DELPESCO THOMAS WAYNE
权利人:DU PONT
摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150 DEG C. to about 500 DEG C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant containing an oxide of lanthanum, samarium, holmium, europium, erbium, yttrium, praseodymium, neodymium, terbium, ytterbium, dysprosium or a mixture of any of them.

专利号:US-3929889-A
优先权日:1971-02-16
标 题 :Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人:SQUIRE EDWARD NOONAN
权利人:DU PONT
摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres.

专利号:US-4001260-A
优先权日:1973-12-19
标 题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
发明人:DEL PESCO THOMAS W
权利人:DU PONT
摘要:An improved process is provided for producing an aromatic amine from ammonia and an aromatic compound which comprises reacting the aromatic compound with ammonia at a temperature of from about 150° C. to about 500° C. and at a pressure of from about 10 to about 1000 atmospheres in the presence of a conditioned nickel/nickel oxide/zirconium oxide cataloreactant which has been treated with ammonia prior to introduction of the cataloreactant to the amination reactants.

专利号:US-4160862-A
优先权日:1972-06-12
标 题 :1-Acyl-3-(amino-lower-alkyl)indoles
发明人:ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

专利号:US-4021431-A
优先权日:1972-06-12
标 题:3-(Piperidino-lower-alkyl)-indoles
发明人:ZENITZ BERNARD L
权利人:STERLING DRUG INC
摘要:1-Acyl-3-(amino-lower-alkyl)indoles, useful as anti-inflammatory agents, are prepared either by acylation of a 3-(amino-lower-alkyl)indole; by Fisher indole synthesis from an N'-acylphenylhydrazine and an amino-lower-alkanone; by alkylation of an amine with a 1-acyl-3-(halo-lower-alkyl)indole; or by reductive alkylation of a 1-acyl-3-indole-lower-alkylcarboxaldehyde.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


摘要:Saito, S., Science of Synthesis, (2004) 7, 37.
摘要:Spitzner, D., Science of Synthesis, (2005) 15, 136.
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