CAS: 280556-71-0; (4-Morpholin-4-Yl-Phenyl)Methanol

上下游产品

CAS号541-41-3 氯甲酸乙酯 | CAS号7470-38-4 4-吗啉基苯甲酸

📜4-(N-吗啉)-苯羧酸甲酯置于氢气,C28H25Brmnn2O2P,Lithium Tert-Butoxide体系中,用 丙醇 用作溶剂,100.0 °C,5.07 Mpa 条件下,反应 12.0H,以91%的收率获得4-(4-吗啉基)苄醇
参考文献:锰催化剂加氢酯类
标题:锰催化剂加氢酯类
摘要:开发了膦-氨基吡啶配体锰络合物催化酯的氢化反应.使用该协议,各种(杂)芳香族和脂肪族羧酸盐(包括生物质衍生的酯和内酯)被氢化成伯醇,产率为 63-98%.发现锰催化剂对苯甲酸甲酯的氢化具有活性,可提供高达 45,000 的周转数 (Ton) 的苯甲醇.对催化剂中间体的研究表明,酰胺锰络合物是该反应的活性催化剂.
Doi:10.1002/adsc.202101376

专利信息

专利号:US-10280189-B2
优先权日:2012-07-17
标题:Method for the synthesis of aminoalkylenephosphonic acid
发明人：BURCK SEBASTIAN; LECLERCQ CEDRIC NICOLAS; NOTTE PATRICK
权利人:MONSANTO TECHNOLOGY LLC
摘要:A method for the synthesis of an aminoalkylenephosphonic acid or its phosphonate esters including the following steps: a) forming, in the presence of an aldehyde or ketone and an acid catalyst, a reaction mixture by mixing a compound having at least one HNR 1 R 2 moiety or a salt thereof, with a compound having one or more P—O—P anhydride moieties, the moieties having one P atom at the oxidation state (+III) and one P atom at the oxidation state (+III) or (+V), wherein the ratio of moles of aldehyde or ketone to N—H moieties is 1 or more and wherein the ratio of N—H moieties to P—O—P anhydride moieties is 0.3 or more, and b) recovering the resulting aminoalkylenephosphonic acid having compound or its phosphonate esters.

专利号:CN-104812766-A
优先权日:2012-07-17
标题:Process for the synthesis of aminoalkylene phosphonic acids

专利号:US-2015225431-A1
优先权日:2012-07-17
标题 :Method for the synthesis of aminoalkylenephosphonic acid

专利号:EP-2875036-A1
优先权日:2012-07-17
标题:Method for the synthesis of aminoalkylenephosphonic acid

专利号:WO-2014012987-A1
优先权日:2012-07-17
标题 :Method for the synthesis of aminoalkylenephosphonic acid

专利号:RU-2694047-C2
优先权日:2012-07-17
标 题:Method for synthesis of aminoalkylene phosphonic acid