CAS: 25895-62-9; Sodium,Cyano(Trideuterio)Boranuide

专利信息

专利号:US-12180182-B2
优先权日:2021-12-01
标题 :(Di)amination of activated allene compounds, derivatives thereof, and methods for synthesis of the same
发明人：DAI MINGJI
权利人:PURDUE RESEARCH FOUNDATION
摘要:One-pot synthesis methods for producing amines from activated allenes and derivatives thereof are provided, as well as the compounds produced thereby.

专利号:US-8933237-B2
优先权日:2012-07-19
标 题:Methods for the synthesis of deuterated vinyl pyridine monomers
发明人：HONG KUNLUN; YANG JUN; BONNESEN PETER V
权利人:UT BATTELLE LLC
摘要:Methods for synthesizing deuterated vinylpyridine compounds of the Formula (1), wherein the method includes: (i) deuterating an acyl pyridine of the Formula (2) in the presence of a metal catalyst and D 2 O, wherein the metal catalyst is active for hydrogen exchange in water, to produce a deuterated acyl compound of Formula (3); (ii) reducing the compound of Formula (3) with a deuterated reducing agent to convert the acyl group to an alcohol group, and (iii) dehydrating the compound produced in step (ii) with a dehydrating agent to afford the vinylpyridine compound of Formula (1). The resulting deuterated vinylpyridine compounds are also described.

专利号:US-2010137244-A1
优先权日:2006-07-13
标题 :Preparation and utility of hmg-coa reductase inhibitors
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.

专利号:US-8658802-B2
优先权日:2012-07-19
标题:Methods for the synthesis of deuterated vinyl pyridine monomers

专利号:US-2014024836-A1
优先权日:2012-07-19
标题 :Methods for the synthesis of deuterated vinyl pyridine monomers

专利号:US-2014213793-A1
优先权日:2012-07-19
标题 :Methods for the synthesis of deuterated vinyl pyridine monomers