CAS: 215523-34-5; 1,8-Naphthyridine-2-Carboxylic Acid

该化合物是一种异环有机化合物,在2位置有一个环球红心核心,并有一个碳酸酸功能组,这种结构在化学和药物应用协调方面具有多功能性,作为合成生物活性分子,特别是抗微生物和抗脉冲剂的关键中间体,其僵硬的芳香框架和染色特性使其在金属-有机框架和催化剂设计中具有价值.复合在标准条件下表现出稳定性,并显示出与进一步功能化的兼容性,能够根据具体的研究或工业需要进行量身定制的修改.其高纯度和定义明确的再活动特征支持合成和药用化学工作流程的可复制结果.

结构式图片

物理性质

MSDS等安全信息

欧盟法规

C&L通报

上下游产品

2-(Trichloromethyl)-1,8-naphthyridine (E)-2-styryl-1,8-naphthyridine 2-methyl-[1,8]naphthyridine (E)-4-(dimethylamino)but-3-en-2-one methyl 1,8-naphthyridine-2-carboxylate [1,8]naphthyridine-2-carboxylic acid [4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide

合成工艺路线路线简述

    📜2-(三氯甲基)-1,8-二氮杂萘置于磷酸体系中,化学反应 3.0H,反应生成1,8-萘啶-2-甲酸
    参考文献:Functionalization Of 2-Methyl-And 2,7-Dimethyl-1,8-Naphthyridine
    标题:Functionalization Of 2-Methyl-And 2,7-Dimethyl-1,8-Naphthyridine
    摘要:
    Doi:10.1021/jo00296A051

    海关参考信息

    专利信息


    专利号:US-2008187575-A1
    优先权日:2004-08-27
    标题:Pyrimidine Derivatives
    发明人：KLEBL BERT; BAUMANN MATTHIAS; HOPPE EDMUND; BREHMER DIRK; DAUB HENRIK; KERI GYORGY; VARGA ZOLTAN; MAROSFALVI JENO; ORFI LASZLO
    权利人:KLEBL BERT; BAUMANN MATTHIAS; HOPPE EDMUND; BREHMER DIRK; DAUB HENRIK; KERI GYORGY; VARGA ZOLTAN; MAROSFALVI JENO; ORFI LASZLO
    摘要:The present invention relates to pyrimidine derivatives, methods for their synthesis, and the use of said pyrimidine derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferation disorders, cancer, leukemia, erectile dysfunction, cardiovascular diseases and disorders, inflammatory diseases, transplant rejection, immunological diseases, neuroimmunological diseases, autoimmune diseases, infective diseases including opportunistic infections, prion diseases and/or neuro-degeneration. Furthermore, the present invention relates to pharmaceutical compositions containing at least one pyrimidine derivative and/or pharmaceutically acceptable salts thereof as an active ingredient together with at least one pharmaceutically acceptable carrier, excipient or diluents as well as to methods for prophylaxis and/or treatment of the above-mentioned diseases and disorders.

    专利号:RU-2120940-C1
    优先权日:1994-06-16
    标题:Derivatives of quinoline- or naphthyridine carboxylic acid and methods of their synthesis

    专利号:NO-318910-B1
    优先权日:1998-12-23
    标 题:Protease inhibitors, method of synthesis and use thereof, and pharmaceutical composition

    其他信息查阅

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    实用工具

    ⚠️全国化工行业净网倡议书
    📋制造商识别码
    📖 海关编码查询
    📝MSDS生成器

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/978-94-017-0761-9_10
    摘要:Treves-Brown KM. Quinolones and Fluoroquinolones. 2000. In: Applied Fish Pharmacology.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知