CAS: 127972-00-3; 2-Methoxy-5-Methylphenylboronic Acid

该化合物是一种碳酸衍生物,通常用作铃木-宫浦交叉相交反应中的关键中间体,这是在有机合成中形成碳-碳债券的一种广泛使用的方法,其甲氧基和甲基替代成分会增强消毒和电子特性,提高混合反应的选择性.该化合物在标准条件下表现出良好的稳定性,并表明与一系列基质相容性,使其在制药和农用化学研究中具有价值.其高纯度和一贯性能确保复杂的合成途径取得可靠结果.建议在惰性条件下适当处理和储存其惰性活性和保存寿命.

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CAS号121-43-7 硼酸三甲酯 | CAS号22002-45-5 3-溴-4-甲氧基甲苯 | CAS号104-93-8 4-甲基苯甲醚(MSO) | CAS号1181294-93-8 2-(2-methoxy-5-... | CAS号259209-21-7 (2-羟基-5-甲基苯基)硼酸 | CAS号71128-89-7 2,6-bis(2-hydro...

合成工艺路线路线简述

    📜在 盐酸体系中,化学反应生成2-甲氧基-5-甲基苯硼酸
    参考文献:Block Copolymers Of Highly Isotactic Polypropylene Via Controlled Ziegler−natta Polymerization
    标题:Block Copolymers Of Highly Isotactic Polypropylene Via Controlled Ziegler−natta Polymerization
    摘要:
    Doi:10.1021/ma048144B

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    专利信息


    专利号:US-10947203-B2
    优先权日:2016-03-25
    标题 :1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor
    发明人:CHEN TAOSHENG; LIN WENWEI; WANG YUEMING
    权利人:ST JUDE CHILDRENS RES HOSPITAL; ST JUDE CHILDRENS RSEARCH HOSPITAL
    摘要:In an aspect, the invention relates to 1,4,5-substituted 1,2,3-triazole and 1,2,4,5-substituted imidazoles having a structure represented by a formula: n nwhich are modulators the pregnane X receptor (“PXRâ€?); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of modulating an adverse drug reaction in a mammal using the compounds and pharmaceutical compositions; methods of treatment of a disorder of uncontrolled cellular proliferation, such as a cancer, using the compounds and pharmaceutical compositions; methods of modulating pregnane X receptor activity in a mammal using the compounds and pharmaceutical compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

    专利号:EP-1836163-B1
    优先权日:2004-12-23
    标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
    发明人:BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
    权利人:NOVARTIS AG
    摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

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    合成参考文献


    参考文献:10.1055/s-2007-969011
    摘要:Stereoselective Palladium-Catalyzed Addition of Boronic Acids onto Aldehydes. Synfacts. 2007 Nov 07;2007(10):1065. doi: 10.1055/s-2007-969011.
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