CAS: 70619-48-6; N-(3-Fluorophenyl)Hydrazinecarbothioamide

该化合物是一种有机化合物,其特征是存在硫磺酰氨基甲氨酯功能组,以其潜在的生物活动而著称;该化合物的特征是氟苯基组,表明芳香环上存在氟化碳原子,这可能影响其化学反应和生物特性;硫酰氨基甲胺因其与金属离子形成协调综合体的能力和展示各种药理活动,包括抗微生物和抗癌特性而经常得到承认;氟丙烯基甲胺的存在可能增强脂性和代谢性稳定性,有可能影响化合物的生物利用率;此外,硫酰氨基氨基苯基甲酸酯可以参与各种化学反应,例如凝聚和环化,使其成为医药化学的一个多用途建筑块.

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上下游产品

CAS号404-72-8 异硫氰酸3-氟苯酯 | CAS号76874-99-2 (3-fluorophenyl... | CAS号3926-62-3 氯乙酸钠 | CAS号372-19-0 3-氟苯胺 | CAS号75-15-0 二硫化碳 | CAS号70618-03-0 3-(3-fluorophen...

合成工艺路线路线简述

    📜(3-氟苯基)氨基二硫代甲酸置于sodium Monochloroacetic Acid,一水合肼体系中,化学反应 4.0H,反应生成 4-(3-氟苯基)-3-氨基硫脲
    参考文献:Synthesis Of New Hyodeoxycholic Acid Thiosemicarbazone Derivatives Under Solvent-Free Conditions Using Microwave
    标题:Synthesis Of New Hyodeoxycholic Acid Thiosemicarbazone Derivatives Under Solvent-Free Conditions Using Microwave
    摘要:An Efficient And Simple Method For Synthesis Of New Hyodeoxycholic Acid Thiosemicarbazone Derivatives Under Solvent-Free Conditions Using Microwave Has Been Developed. Its Main Advantages Are Short Reaction Times,Good Conversions And The Environmentally Friendly Nature Of The Process. The Preliminary Results Indicate That Some Of These Compounds Possess Inhibitory Effects Against E. Coli. (C) 2010 Zhi Gang Zhao. Published By Elsevier B.V. On Behalf Of Chinese Chemical Society. All Rights Reserved.
    DOI:10.1016/j.Cclet.2010.10.020

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    合成参考文献


    参考文献:10.1107/s1600536810034951
    摘要:Ramzan M, Pervez H, Tahir MN, Yaqub M. 4-(3-Fluoro-phen-yl)-1-(2-oxoindolin-3-yl-idene)thio-semicarbazide. Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 04;66(Pt 10):o2494–5.
    参考文献:10.1016/j.ejmech.2014.05.044
    摘要:Serra S, Moineaux L, Vancraeynest C, Masereel B, Wouters J, Pochet L, Frédérick R. Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties. European Journal of Medicinal Chemistry. 2014 Jul;82():96–105. doi: 10.1016/j.ejmech.2014.05.044.
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