CAS: 617-57-2; 2-((2-Hydroxypropanoyl)Oxy)Propanoic Acid

该化合物是盐或酯酸,通常在酸与碱或酒精发生反应时形成; 常见于各种生物系统,特别是在厌氧呼吸期间肌肉新陈代谢中; 该化合物的特征是能够起到缓冲剂的作用,帮助保持生物液体中的pH值; 酸性乳酸酯在水中溶解,有利于其在代谢过程中发挥作用; 通常用于食物保存,并且由于酸性较轻而用作调味剂; 此外,它在化妆品工业中应用其润滑性特性和药物作为稳定剂或防腐蚀剂; 一般认为,该化合物在适当使用时是安全的,但应对其浓度和使用进行监测,以避免潜在的不利影响.

结构式图片

合成工艺路线路线简述

    乳酸 反应 2.0H,反应生成 2-羟基丙酸-1-羰乙酯
    参考文献:一种呋喃二甲酰-聚羟基酸酯增塑剂及其应用
    标题:一种呋喃二甲酰-聚羟基酸酯增塑剂及其应用
    摘要:本发明公开了一种呋喃二甲酰‑聚羟基酸酯增塑剂及其应用.该呋喃二甲酰‑聚羟基酸酯增塑剂由三部分组成:呋喃二甲酸部分,由羟基酸低聚化形成的聚酯部分和末端封端醇部分.该增塑剂可以应用在聚合物增塑方面,特别在pvc中表现出非常好的相容性和增塑效率.同时,该增塑剂所需原料来源均可来源于生物质,具有较好的可再生性.

    海关参考信息

    专利信息


    专利号:US-2011263720-A1
    优先权日:2010-03-09
    标 题 :Synthesis of alpha-tocopherolquinone derivatives, and methods of using the same
    发明人:PAISLEY STEVEN D; LEPREE JASON M; HAWI AMALE; ECKHOFF MICHAEL
    权利人:PENWEST PHARMACEUTICALS CO
    摘要:The present invention is directed to a method of synthesizing a compound of Formula I: n n n n n n n n n n the method comprising oxidizing alpha-tocopherol with a metal salt oxidizing agent to form the compound of Formula I, wherein the stoichiometric ratio (mol/mol) of metal salt oxidizing agent/alpha-tocopherol is 1.6 to 4. The invention is also directed to a method of synthesizing a compound of Formula I, the method comprising (a) hydrolyzing alpha-tocopheryl acetate in the presence of a base; (b) neutralizing the hydrolyzing of (a), thereby forming alpha-tocopherol; and (c) oxidizing the alpha-tocopherol of (b) with a metal salt oxidizing agent to form the compound of Formula I, wherein the stoichiometric ratio (mol/mol) of metal salt oxidizing agent/alpha-tocopherol is 1.6 to 4.

    专利号:US-8895760-B2
    优先权日:2010-02-26
    标 题 :Process for the preparation of L-lactide of high chemical yield and optical purity
    发明人:IDAGE BHASKAR BHAIRAVNATH; IDAGE SUSHEELA BHASKAR; SWAMINATHAN SIVARAM
    权利人:IDAGE BHASKAR BHAIRAVNATH; IDAGE SUSHEELA BHASKAR; SWAMINATHAN SIVARAM; COUNCIL SCIENT IND RES
    摘要:A process for the synthesis of 100% optically pure L(+)-lactide catalyzed by zinc and tin metal catalysts of less than 150 micron particle size is disclosed. The L-lactide obtained was further purified to obtain lactide of 100% optical purity and acid impurities less than 10 meq/kg.

    专利号:US-2011269201-A1
    优先权日:2010-04-30
    标题:Redirected bioenergetics in recombinant cellulolytic clostridium microorganisms
    发明人:GRAY KEVIN; O'MULLAN PATRICK
    权利人:QTEROS INC
    摘要:Compositions and methods are provided for redirecting metabolic solventogenesis pathways to enhance the product yield from fermentation of biomass. Clostridium microorganism pathways are modified to extend the growth phase and prevent inhibition of acetaldehyde while bypassing the synthesis of acetyl CoA.

    专利号:WO-2011112679-A1
    优先权日:2010-03-09
    标题 :Synthesis of alpha-tocopherolquinone derivatives, and methods of using the same

    专利号:WO-2013160485-A1
    优先权日:2012-04-28
    标 题 :Process for continuous preparation of lactide directly from concentrated lactic acid
    发明人:HOELDERLICH WOLFGANG; VENSCHOTT MORITZ
    权利人:UHDE INVENTA FISCHER GMBH
    摘要:The subject-matter of the present invention relates to a process for the continuous, heterogeneously catalysed, direct preparation of L-lactide from concentrated lactic acid. The aim is to circumvent the process steps of the known prepolymerization and subsequent depolymerization, and to reduce them to one synthesis step. Furthermore, the by-products and the racemization are minimized, and so high-purity L-lactide is prepared.

    专利号:WO-9846763-A1
    优先权日:1997-04-11
    标题:Methods and compositions for synthesis of long chain polyunsaturated fatty acids
    湖北兴琰新材料科技有限公司
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    合成参考文献


    参考文献:10.1107/s0108270110026193
    摘要:Lutz M, Krieken JV. (S,S)-Lactoyllactic acid and (S,S,S)-lactoyllactoyllactic acid. Acta Crystallogr C Cryst Struct Commun. 2010 Jul 08;66(8):o401–5. doi: 10.1107/s0108270110026193.
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