CAS: 46032-98-8; (1R,2R)-2-Amino-1-Phenylpropane-1,3-Diol
该化合物是有机化合物,其特征是手性结构,包括氨基氨基组和两个附于丙烷基骨的氢氧基组,该化合物一般在室温固态中发现,由于存在可进行氢联结的氢氧化基组,极地溶剂中可溶解.该苯组助长其疏水性,影响其整体溶解性和再活动.作为氨基酒精,它可以参与各种化学反应,包括典型的氨基胺和酒精,使其成为有机合成中有价值的中间体.其立体化学作用很大,因为(1R,2R)配置可影响其生物活动和其他分子的相互作用.该化合物可用于制药应用,特别是开发需要特定立体化学特性的药物,从而产生功效.应当参考安全数据,以便处理和使用,以及所有化学物质.
- 英文名称(1R,2R)-2-Amino-1-Phenylpropane-1,3-Diol
- 中文名称(1R,2R)-(-)-2-氨基-1-苯基-1,3-丙二醇
- IUPAC名称(1R,2R)-2-amino-1-phenylpropane-1,3-diol
- 其它别名2-氨基-1-苯基-1,3丙二醇; (R(R*,R*))-2-Amino-1-Phenylpropane-1,3-Diol
- CAS编号46032-98-8
- MFCD编号:MFCD00069617
- EINECS号:256-250-8
- FDA UNII编号:7Q33891T0E
- 分子式:C9H13NO2分子量:167.208
- 产品CID: 1460618
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号849357-84-2 methyl (2S,3R)-... | CAS号100-52-7 苯甲醛 | CAS号104320-68-5 trans-4-(methox... | CAS号127181-72-0 anti-(4S,2'S,3'... | CAS号112459-60-6 (4S)-4-isopropy... | CAS号115794-67-7 Oxiranecarboxyl... | CAS号849357-83-1 methyl (2R,3R)-... | CAS号3306-06-7 1S,2S-(+)-2-ami... | CAS号1009093-14-4 B°C-D-threo-3-p... | CAS号56-75-7 氯霉素 | CAS号119-62-0 1-对硝基苯基-2-氨基-1,3-丙二醇合成工艺路线路线简述
📜Anti-(4S,2'S,3'S)-3-(3'-Hydroxy-3'-Phenyl-2'-Bromo-1'-Oxopropyl)-4-(1-Methylethyl)-2-Oxazolidinone置于palladium On Activated Charcoal 锂硼氢,Sodium Azide,氢气体系中,用 四氢呋喃,甲醇,N,N-二甲基甲酰胺 作为反应溶剂,25.0 °C,101.33 Kpa 条件下,反应 19.0H,反应生成 (1R,2R)-(-)-2-氨基-1-苯基-1,3-丙二醇
参考文献:Stereoselective Syntheses Of (−)-Chloramphenicol And (+)-Thiamphenicol
标题:Stereoselective Syntheses Of (−)-Chloramphenicol And (+)-Thiamphenicol
摘要:Chloramphenicol And Thiamphenicol Have Been Enantioselectively Synthesized Using An Asymmetric Halohydrin Reaction As A Key Step. In Particular,Halomethoxylation Reaction Was Used,Where O-Methyl Functions As A Hydroxyl Protecting Group And Eliminates An Additional Protection Step. (C) 2006 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Tet.2006.07.014
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905399001-1,3-丙二醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-5248815-A
优先权日:1991-12-27
标 题 :Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
发明人：PARADIES HENRICH H
权利人:PARADIES HENRICH H
摘要:The present invention relates to a stereospecific chemical synthesis of optically pure enantiomers of 2-aryl-alkanoic acids, especially those of the biologically active (S)-aryl-propionic acids, in good chemical yields, useful for preparing large quantities thereof, and having a high optical purity.
专利号:EP-0641304-B1
优先权日:1991-12-27
标题:Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
专利号:EP-0641304-A1
优先权日:1991-12-27
标题 :Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
专利号:DE-69225075-T2
优先权日:1991-12-27
标题 :STEREOSELECTIVE SYNTHESIS OF 2-ARYLPROPIONIC ACIDS HIGH OPTICAL PUREITY USING CHIRAL OXAZOLINES
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1055/a-1743-4534
摘要:Dhayalan V, Dandela R, Devi KB, Dhanusuraman R. Synthesis and Applications of Asymmetric Catalysis Using Chiral Ligands Containing Quinoline Motifs. SynOpen. 2022 Feb;06(01):31–57. doi: 10.1055/a-1743-4534.
📝 需求与反馈
尽可能描述清楚需求与问题信息
