CAS: 385384-24-7; Methyl (7As,11S,12R,13Ar,13Bs)-11,13B-Dimethyl-14-Oxo-3,4,6,7,7A,8,10,11,12,13,13A,13B-Dodecahydro-1,12-Methanopyrano[2',3',4':8,1]Azuleno[4,5-A]Indolizine-2-Carboxylate

英文名称Methyl (7As,11S,12R,13Ar,13Bs)-11,13B-Dimethyl-14-Oxo-3,4,6,7,7A,8,10,11,12,13,13A,13B-Dodecahydro-1,12-Methanopyrano[2',3',4':8,1]Azuleno[4,5-A]Indolizine-2-Carboxylate
中文名称达菲环素D
IUPAC名称methyl (7aS,11S,12R,13aR,13bS)-11,13b-dimethyl-14-oxo-3,4,6,7,7a,8,10,11,12,13,13a,13b-dodecahydro-1,12-methanopyrano[2',3',4':8,1]azuleno[4,5-a]indolizine-2-carboxylate
其它别名Daphnicyclidin D; Daphnicyclidine D; 1,12-Methanopyrano[4',3',2':1,8]Azuleno[4,5-A]Indolizine-2-Carboxylic Acid, 3,4,6,7,7A,8,10,11,12,13,13A,13B-Dodecahydro-11,13B-Dimethyl-14-Oxo-, Methyl Ester, (7As,9S,11S,12R,13Ar,13Bs)-
CAS编号385384-24-7
MFCD编号:MFCD28386002
分子式:C23H27NO4分子量:381.47
产品CID: 1397672
产品分类有机原料 → 碳氢化合物 → 不饱和烃

相似结构搜索
InChIKey: DTNVJGYTJYNCDT-UHCAAFETSA-N
InChI=1S/C23H27NO4/c1-11-9-24-10-12-4-5-15-17-13(6-7-28-15)18(22(26)27-3)19-20(17)23(12,2)16(24)8-14(11)21(19)25/h11-12,14,16H,4-10H2,1-3H3/t11-,12-,14-,16-,23-/m1/s1
计算化学: 氢键受体数5.0氢键供体数*可旋转键数2.0

MSDS等安全信息

危险描述H303 May be harmful if swallowed+H313 Skin contact may be harmful+H333 Inhalation may be harmful to the body
防范说明P264+P280+P305+P351+P338+P337+P313
安全声明H303+H313+H333

上下游产品

methanol daphnicyclidin H

合成工艺路线路线简述

📜双水杨酯h置于对甲苯磺酸体系中,用甲醇,氯仿作为反应溶剂,化学反应 24.0H,以0.7 Mg的收率获得产物达菲环素d
参考文献:Daphnicyclidins A−h,Novel Hexa-Or Pentacyclic Alkaloids From Two Species Of Daphniphyllum
标题:Daphnicyclidins A−h,Novel Hexa-Or Pentacyclic Alkaloids From Two Species Of Daphniphyllum
摘要:Eight Highly Modified Daphniphyllum Alkaloids With Unprecedented Fused Hexa-Or Pentacyclic Skeletons,Daphnicyclidins A-H (1-8),Have Been Isolated From The Stems Of Daphniphyllum Humile And D. Teijsmanni,And Their Structures Were Elucidated On The Basis Of Spectroscopic Data And Chemical Means. The Stereochemistry Was Elucidated By Combination Of Noesy Correlations,X-Ray Crystallographic Data,And Cd Analyses.
DOI:10.1021/ja016955E