专利号:US-5194562-A 优先权日:1989-02-22 标题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers 发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J 权利人:DOW CHEMICAL CO 摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rob PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.
专利号:US-5216110-A 优先权日:1989-02-22 标题 :Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers 发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J 权利人:DOW CHEMICAL CO 摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rod PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.
专利号:US-5104960-A 优先权日:1989-02-22 标 题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers 发明人:INBASEKARAN MUTHIAH N; MULLINS MICHAEL J 权利人:DOW CHEMICAL CO 摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rod PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.
专利号:US-7067554-B2 优先权日:2000-05-30 标 题 :Method for the synthesis of compounds of formula I and their uses thereof 发明人:MJALLI ADNAN M M; GOPALASWAMY RAMESH; AVOR KWASI A; WYSONG CHRISTOPHER L; ANDREW PATRON 权利人:TRANSTECH PHARMA INC 摘要:This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the invention are useful as modulators of the interaction between the receptor for advanced glycated end products (RAGE) and its ligands, such as advanced glycated end products (AGEs), S100/calgranulin/EN-RAGE, β-amyloid and amphoterin, and for the management, treatment, control, or as an adjunct treatment for diseases in humans caused by RAGE. Such diseases or disease states include acute and chronic inflammation, the development of diabetic late complications such as increased vascular permeability, nephropathy, atherosclerosis, and retinopathy, the development of Alzheimer's disease, erectile dysfunction, and tumor invasion and metastasis.
专利号:AU-2005200425-A1 优先权日:2000-05-30 标题 :A method for the synthesis of compounds of formula 1 and their uses thereof
专利号:US-2006189578-A1 优先权日:2000-05-30 标题:Method for the synthesis of compounds of formula I and their uses thereof