CAS: 3433-80-5; 2-Bromobenzyl Bromide

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CAS号18982-54-2 2-溴苄醇 | CAS号95-46-5 2-溴甲苯 | CAS号6630-33-7 2-溴苯甲醛 | CAS号850335-71-6 2-bromo-1-[(eth... | CAS号94236-21-2 1-溴-2-((甲氧基甲氧基)甲基)苯 | CAS号88-65-3 邻溴苯甲酸 | CAS号610-94-6 2-溴苯甲酸甲酯 | CAS号100-39-0 溴化苄 | CAS号7726-95-6 溴素 | CAS号7791-25-5 磺酰氯 | CAS号1075-28-1 1-溴-2-(3-溴丙基)苯 | CAS号112169-51-4 (2-bromophenyl)... | CAS号1074-15-3 1-溴-2-(2-溴乙基)苯 | CAS号109638-02-0 N-tert-butyl-2-... | CAS号106020-70-6 2-(甲氧基甲基)苯甲醛 | CAS号52711-30-5 1-溴-2-(甲氧基甲基)苯 | CAS号34824-58-3 2-溴苯甲醛乙烯醛 | CAS号91130-51-7 4-(2-溴苯甲基)吗啉 | CAS号36926-82-6 2-氧代-1,2-二氢喹啉-3-腈 | CAS号90841-47-7 2-溴苯丁酸

甲苯置于oxone,水,Potassium Bromide体系中,用 二氯甲烷,乙腈 用作溶剂,化学反应 40.0H,反应生成2-溴溴苄
参考文献:室温下溴化钾//酮在可见光驱动下氧化苯甲酰sp3 C-h键的氧化单溴和二溴化作用
标题:室温下溴化钾//酮在可见光驱动下氧化苯甲酰sp3 C-h键的氧化单溴和二溴化作用
摘要:◊ Mz和ml同等贡献这项工作. 抽象的 在室温下可见光下,在水/二氯甲烷中使用oxone作为氧化剂,已成功地用溴化钾溴化了苯甲酸sp 3 C-h键.带有吸电子基团的甲苯,乙苯和其他烷基苯,例如br,Cl,Come,Co 2 Et,Co 2 H,Cn或no 2在该反应中,以非常好或优异的收率提供相应的苄基一溴化物.在过量的溴化钾存在下,也可以在延长的反应时间内生成二溴化物.控制可见光(〜500 Lux)的照度对于实现这些溴化物的高产率和高选择性至关重要.一氟化物和二氟化物可以通过用氟化钾对苄基溴化物进行亲核取代而方便地制备. 在室温下可见光下,在水/二氯甲烷中使用oxone作为氧化剂,已成功地用溴化钾溴化了苯甲酸sp 3 C-h键.带有吸电子基团的甲苯,乙苯和其他烷基苯,例如br,Cl,Come,Co 2 Et,Co 2 H,Cn或no 2在该反应中,以非常好或优异的收率提供相应的苄基
Doi:10.1055/s-0037-1610651

专利信息

专利号:US-7102023-B2
优先权日:1999-11-24
标 题:Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
发明人：BUCHWALD STEPHEN L; PLANTE OBADIAH J; SEEBERGER PETER H
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:One aspect of the present invention relates to optionally substituted halogenated benzyl halides and the like. These compounds are useful as halogenated benzyl ether-based protecting groups for a variety of functional groups. Another aspect of the present invention relates to use of said protecting groups in an orthogonal protecting group strategy for the synthesis of complex molecules that comprise a number of suitable functional groups. Another aspect of the present invention relates to saccharides bearing various arrays of protecting groups of the present invention. Another aspect of the present invention relates to a method of synthesizing an oligosaccharide or glycoconjugate, comprising the steps of: using a saccharide bearing at least one protecting group of the present invention to glycosylate a second molecule to give a product comprising said saccharide; and removing a protecting group of the present invention from said product.

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-5068360-A
优先权日:1990-01-25
标题 :Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom
发明人：DEHOFF BRADLEY S
权利人:SYNTEX INC
摘要:An improved process for the synthesis of 2-(2'-thienyl)ethylamine from suitably functionalized derivatives of 2-(2'-thienyl)ethanol employing ammonia gas in the presence of a metal salt or liquid ammonia and alkyl ketone as a solvent. The 2-(2'-thienyl)ethylamine produced by this process is advantageously converted to ticlopidine.

专利号:US-5191090-A
优先权日:1990-01-25
标题:Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom
发明人：DEHOFF BRADLEY S
权利人:SYNTEX INC
摘要:An improved process for the synthesis of 2-(2'-thienyl)ethylamine from suitably functionalized derivatives of 2-(2'-thienyl)ethanol employing ammonia gas in the presence of a metal salt or liquid ammonia and alkyl ketone as a solvent. The 2-(2'-thienyl)ethylamine produced by this process is advantageously converted to ticlopidine.

专利号:EP-0946478-B1
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehydes, ketones and hydroxamic acid compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to processes for the solid-phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.