CAS: 174484-84-5; Magnesium,N,N-Bis(Trimethylsilyl)Aniline,Chloride
该化合物是一种在有机合成中使用的高度活性Griignard试剂,特别是用于将三[双(三甲基硅)基)联苯组引入目标分子.三甲基硅基(TMS)组增强了稳定性和溶性,使试剂适合于受控反应.该溶液通常用醚溶剂(例如,THF或二乙醚)制成,对于构建复杂的芳香框架很有价值,包括制药和先进材料.其空气和湿气敏感性质要求在惰性条件下处理.再生剂在形成碳和碳热解质债券方面的选择性和效率使得在研究和工业应用中精确合成成为首选.
物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
专利信息
专利号:US-2010184989-A1
优先权日:2007-03-12
标 题 :De Novo Synthesis of Conjugates
发明人：RIGGS-SAUTHIER JENNIFER; DENG BO-LIANG; REN ZHONGXU; ZHANG WEN; GU XUYUAN; DUARTE FRANCO J
权利人:NEKTAR THERAPEUTICS
摘要:The invention provides methods for the preparation of small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer obtained from a water-soluble oligomer composition. Such drugs are produced through modification of a synthetic pathway to attach the oligomer to an intermediate compound followed by completion of the synthetic path.
专利号:AU-2008226820-A1
优先权日:2007-03-12
标题 :De novo synthesis of conjugates
专利号:CA-2679473-A1
优先权日:2007-03-12
标题:De novo synthesis of conjugates
专利号:EP-2125027-A2
优先权日:2007-03-12
标题:De novo synthesis of conjugates
专利号:WO-2008112286-A2
优先权日:2007-03-12
标题:De novo synthesis of conjugates
专利号:JP-2010521465-A
优先权日:2007-03-12
标 题 :De novo synthesis of complex
