2-甲基丁酸,正丁醇置于吡啶,4-二甲氨基吡啶,N,N'-二环己基碳二亚胺体系中,用 二氯甲烷 用作溶剂,化学反应 3.5H,以69.6%的收率获得2-甲基丁酸丁酯
参考文献:Nematicidal Activity Of Natural Ester Compounds And Their Analogues Against Pine Wood Nematode,Bursaphelenchus Xylophilus
标题:Nematicidal Activity Of Natural Ester Compounds And Their Analogues Against Pine Wood Nematode,Bursaphelenchus Xylophilus
摘要:In This Study,We Evaluated The Nematicidal Activity Of Natural Ester Compounds Against The Pine Wood Nematode,Bursaphelenchus Xylophilus,To Identify Candidates For The Development Of Novel,Safe Nematicides. We Also Tested The Nematicidal Activity Of Synthesized Analogues Of These Ester Compounds To Determine The Structure-Activity Relationship. Among 28 Ester Compounds Tested,Isobutyl 2-Methylbutanoate,3-Methylbutyl 2-Methylbutanoate,3-Methylbutyl Tiglate,3-Methyl-2-Butenyl 2-Methylbutanoate,And Pentyl 2-Methylbutanoate Showed Strong Nematicidal Activity Against The Pine Wood Nematode At A 1 Mg/ml Concentration. The Other Ester Compounds Showed Weak Nematicidal Activity. The Lc50 Values Of 3-Methylbutyl Tiglate,Isobutyl 2-Methylbutanoate,3-Methylbutyl 2-Methylbutanoate,3-Methyl-2-Butenyl 2-Methylbutanoate,And Pentyl 2-Methylbutanoate Were 0.0218,0.0284,0.0326,0.0402,And 0.0480 Mg/ml,Respectively. The Ester Compounds Described Herein Merit Further Study As Potential Nematicides For Pine Wood Nematode Control.
Doi:10.1021/jf503631E