CAS: 126429-21-8; Diallyl Diisopropylphosphoramidite

相似化合物

102690-88-0 137348-86-8 117924-33-1

上下游产品

(allyloxy)bis(diisopropylamino)phosphine allyl alcohol diisopropylamine(S)-3-(Bis-allyloxy-phosphoryloxy)-2-((S)-2-phenylacetylamino-propionylamino)-propionic acid tert-butyl ester (2S,3R)-3-(Bis-allyloxy-phosphoryloxy)-2-((S)-2-phenylacetylamino-propionylamino)-butyric acid tert-butyl ester (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-2-phenylacetylamino-propionylamino)-propionylamino]-propionic acid tert-butyl ester

二异丙胺置于吡啶,二异丙基铵盐四氮唑,三氯化磷体系中,用 二氯甲烷 用作溶剂,化学反应 5.5H,反应生成己二烯 N,N-二异丙基亚磷酰胺
参考文献:Bis(Allyloxy)(Diisopropylamino)Phosphine As A New Phosphinylation Reagent For The Phosphorylation Of Hydroxy Functions
标题:Bis(Allyloxy)(Diisopropylamino)Phosphine As A New Phosphinylation Reagent For The Phosphorylation Of Hydroxy Functions
摘要:
Doi:10.1016/s0040-4039(01)80694-8

专利信息

专利号:US-6790946-B2
优先权日:1997-05-14
标题 :Synthesis of oligonucleotides
发明人：KWIATKOWSKI MAREK; LANDEGREN ULF; NILSSON MATS
权利人:QUIATECH AB
摘要:A method of preparing an immobilized oligonucleotide having a free 3′-end comprises the steps of: i) preparing an oligonucleotide attached in a first position to a solid support via its 3′-end and having a free 5′-end; ii) binding said oligonucleotide in a second position remote from the 3′-end to the solid support; and iii) selectively releasing the 3′-end of the oligonucleotide from the solid support to obta the oligonucleotide attached to the support in said second position in a reversed orientation with a free 3′-end.

专利号:US-2002051994-A1
优先权日:1997-05-14
标题 :Synthesis of oligonucleotides

专利号:US-2025170267-A1
优先权日:2022-02-28
标 题 :Antibody-drug conjugate precursor and intermediate for synthesis thereof
发明人：TSUZAKI YASUNORI; MIZUNO GEN; KASHIWAGI TAKAMASA; TANAKA MASAYUKI; SHIMIZU HAYATO; NONOUCHI SHIMPEI; MATSUSHITA TAKASHI; KIMURA TOMIO
权利人:UBE CORP
摘要:A method for improving the stability of an antibody-drug conjugate in a living body, and a conjugate precursor for producing a stabilized antibody-drug conjugate. An antibody-drug conjugate precursor represented by the following general formula (I) or a salt thereof, a synthetic intermediate thereof or a salt thereof, n Z-L-D  (I)n n where Z is a reactive group which can react with a functional group present in an antibody or a modified antibody; D is an antitumor drug residue in which one hydrogen atom or one hydroxy group is removed from any position of an antitumor drug molecule or an analog thereof or a derivative thereof; L is a linker which links Z to D; and at least any one of D and L has one or more lactonyl group(s) at any position(s) as substituent(s) or protecting group(s).

专利号:EP-0983288-B1
优先权日:1997-05-14
标 题 :Synthesis of oligonucleotides

专利号:WO-9851698-A1
优先权日:1997-05-14
标题:Synthesis of oligonucleotides

专利号:JP-2005206605-A
优先权日:1997-04-11
标 题:Process for the synthesis of phosphodiesters