CAS: 101-61-1; Bis[4-(Dimethylamino)Phenyl]Methane

相似化合物

90-94-8 1226-46-6 135-91-1

上下游产品

3-chlorobenzoic 2-cyclopropylacetic peroxyanhydride N,N-dimethyl-anilineN,N-dimethyl-aniline formic acid 4,4'-bis(dimethylamino)benzhydrol auramine O bis(p-dimethylaminophenyl)methanone N,N-dimethyl-4-(4-nitrophenylazo)aniline bis-[4-(cyano-methyl-amino)-phenyl]-methane

米氏酮置于四乙基溴化铵,三苯基膦体系中,用 乙腈 用作溶剂,化学反应 8.0H,以65%的收率获得双[4-(二甲氨基)苯基]甲烷
参考文献:酮的电化学脱氧还原
标题:酮的电化学脱氧还原
摘要:通过配对电解的电化学还原已被用于实现酮的脱氧还原.由于酮与阳极氧化产生的三苯基膦自由基阳离子络合,羰基的还原很容易发生.通过磷酰基自由基的自发β-断裂,C-O键被裂解形成苄基自由基中间体.这些自由基物质要么能够从 Mecn 中提取氢,要么在阴极进行还原以产生碳负离子,后处理形成酮的还原氢化.
Doi:10.1039/d2Cc04548F

专利信息

专利号:US-2009318592-A1
优先权日:2005-10-11
标 题 :Process for the Synthesis of Amine Ethers
发明人：FREY MARKUS; BROENNIMANN VALERIE
权利人:CIBA GEIGY CORP
摘要:The present invention relates to novel processes for the preparation of a sterically hindered amine ether by reacting a corresponding sterically hindered amine oxide with a ketone or an aldehyde with at least one reactive H in the presence of a peroxydisulphate. Products obtained by this process may be hydrogenated. The compounds made by these processes are particularly effective in the stabilization of polymer compositions against harmful effects of light, oxygen and/or heat and as flame-retardants for polymers.

专利号:WO-2009047354-A1
优先权日:2007-10-12
标题:Chemo-enzymatic synthesis of a c-terminal thioester of an amino acid or a peptide
发明人：QUAEDFLIEG PETER JAN LEONARD MARIO; MERKX NICOLAAS SEBASTIAAN MICHEL
权利人:DSM IP ASSETS BV; QUAEDFLIEG PETER JAN LEONARD M; MERKX NICOLAAS SEBASTIAAN MICH
摘要:The present invention relates to a method for synthesising a C-terminal thioester of an N-protected amino acid or an optionally N-protected oligopeptide, comprising reacting a thiol with a compound selected from optionally N-protected amino acids, amino acid C-terminal esters (other than the ester to be synthesised) and optionally N-protected oligopeptide C-terminal esters (other than the ester to be synthesised) in the presence of a hydrolytic enzyme, thereby forming the thioester.

专利号:US-2007191516-A1
优先权日:2004-03-15
标题 :Process for the synthesis of amine ethers
发明人：FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS
权利人:FREY MARKUS; RAST VALERIE; BRAIG ADALBERT; KRAMER ANDREAS
摘要:A process for the preparation of a sterically hindered amine ether which comprises reacting a corresponding sterically hindered aminoxide with a C 5 -C 18 alk-1-ene in the presence of an organic hydroperoxide and optionally hydrogenating the resulting product as well as the product mixtures obtained therewith and their use as stabilizers and flame retardants.

专利号:US-2005080260-A1
优先权日:2003-04-22
标 题 :Preparation of prodrugs for selective drug delivery
发明人：MILLS RANDELL L; WU GUO-ZHANG
摘要:Synthesis of a chemical compound having the formula A-B-C that may serve for applications such as drug delivery where A is a chemiluminescent, moiety, B is a photochromic moiety, and C is a biologically active moiety where A-B-C may serve as a prodrug. Novel synthetic methods of the present invention to form the prodrug comprised the steps of (1) forming a benzophenone, (2) forming a diaryl ethylene, (3) attaching a phthalimide moiety to at least one of the aryl groups of the ethylene to form a phthalimide-ethylene conjugate, (4) condensing two ethylene-phthalimide conjugates to form a phthalimide-pentadiene conjugate, (5) converting the phthalimide to the phthalhydrazide by reaction with hydrazine to form a carrier compound according to the present invention, and (6) reacting the carrier compound with an nucleophilic moiety of the drug to form the corresponding prodrug. Alternatively the carrier can be prepared by using the halo-substituted diaryl ethylene to make the corresponding cationic leuco dye-like compound with known methods. The cationic compound then is protected by reacting with a nucleophile and coupled with the aminophathalimide by palladium-catalyzed amination to form the protected phthalimide-pentadiene conjugate. The latter is refluxed with hydrazine to convert its phthalimide to the phthalhydrazide and acidified to give the carrier. An additional aspect of the present invention relates to the use of these compounds as antiviral agents for the treatment of viral infections such as HIV and as anticancer agents for the treatment of cancers such as bowel, lung, and breast cancer.

专利号:US-3943142-A
优先权日:1969-01-24
标 题:Dye intermediates and their preparation and use in the synthesis of methine dyes
发明人：OWEN JOHN R
权利人:EASTMAN KODAK CO
摘要:Compositions of matter are provided comprising a stable, non-vaporous monomeric methylene base selected from a 2-methylenethiazoline; a 2-methylenebenzothiazoline; a 2-methylenenaphthothiazoline; a 2-methylenebenzoselenazoline; and a 2-methylenenaphthoselenazoline. The compositions of the invention are prepared by reacting the parent 2-methyl quaternary salt with a non-hydroxylic base which removes a proton of the heterocyclic salt together with a proton acceptor which inhibits build-up of the hydro salt of the non-hydroxylic base, the reaction being conducted under anhydrous conditions in a non-hydroxylic liquid in which the heterocyclic quaternary salt is sufficiently insoluble to inhibit dimer formation. The compositions of the invention are employed in the preparation of methine dyes.

专利号:US-11406964-B2
优先权日:2018-03-28
标题 :Heterogeneous catalysts for the synthesis of carbamates
发明人：WERSHOFEN STEFAN; VIDAL-FERRAN ANTON; RICO JOSÉ LUIS NÚÑEZ; PEREZ-RAMIREZ JAVIER; PUERTOLAS LACAMBRA BEGONA; AMRUTE AMOL P
权利人:COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG
摘要:The present invention relates to a catalyst for preparing carbamates, in particular aromatic carbamates, comprising a binary oxide having the formula L1-xMxO2, wherein L is a metal selected from the lanthanoid series and M is a metal selected from the group consisting of Sc, Y, Ti, Zr, Hf, metals from the lanthanoid series and metals from the actinoid series, and wherein x ranges from 0.01 to 0.05. The present invention also relates to a method for producing said catalysts and a method of utilizing said catalysts in the production of carbamates, in particular aromatic carbamates.