CAS: 943722-24-5; Tert-Butyl ((5-Bromopyridin-3-yl)Methyl)Carbamate

该化合物是属于氨基甲酸类的化合物,其特点是碳基酸功能组,其特点是与氮原子(N)相连的碳基(C=O)组存在,该原子也与烷基或丙烯基组有联系;该特定结构包括5-溴-3-丙烯基甲基酯,表明在基环上存在溴基,有助于其生物活动和药用化学的潜在应用;该1,1-二甲基乙基酯组表明该化合物具有大宗的替代成分,可能会影响其溶性与再活性;一般来说,氨基甲基苯可展示一系列生物活动,包括杀虫和乙基酰特性,还可作为药物合成的中间体;与许多化学物质一样,应观测到安全性和处理防范措施,因为其具有潜在的毒性和环境影响.

英文名称Tert-Butyl ((5-Bromopyridin-3-yl)Methyl)Carbamate
中文名称叔丁基((5-溴吡啶-3-基)甲基)氨基甲酸酯
IUPAC名称tert-butyl ((5-bromopyridin-3-yl)methyl)carbamate
其它别名((5-溴吡啶-3-基)甲基)氨基甲酸叔丁酯; 3-(N-Boc-Aminomethyl)-5-Bromopyridine
CAS编号943722-24-5
MFCD编号:MFCD10700149
EINECS号:691-289-8
分子式:C11H15BrN2O2分子量:287.15
产品CID: 1993928
产品分类有机原料→分子砌块→芳杂环类化合物→吡啶类化合物

相似结构搜索
InChIKey: VZPOHASZICQBDX-UHFFFAOYSA-N
InChI=1S/C11H15BrN2O2/c1-11(2,3)16-10(15)14-6-8-4-9(12)7-13-5-8/h4-5,7H,6H2,1-3H3,(H,14,15)
计算化学: 氢键受体数3.0氢键供体数1.0可旋转键数2.0

相似化合物

135124-70-8 1001414-82-9 864266-29-5

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Warning(警告)
危险描述H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P264-P280-P302+P352-P362

欧盟法规

ECHA物质C&L通报

上下游产品

3-氨甲基-5-溴吡啶 (5-Bromopyridin-3-yl)Methanamine 135124-70-8

合成工艺路线路线简述

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Triethylamine Solvents: Methanol; 0 °C; 2 H,25 °C
标题:Preparation Of Immunoconjugates Containing An Anti-Cea Antibody Linked By Conjugation To One Or More 8-Heterocyclyldiyl- And 8-Heteroaryldiyl-2-Aminobenzazepine Derivatives Useful In Treating Cancer
参考文献:World Intellectual Property Organization]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Sodium Bicarbonate Solvents: Tetrahydrofuran,Water; 0 °C; 2 H,Rt
标题:Pleuromutilin Derivatives,And Pharmaceutical Compositions,Synthetic Method And Use Thereof For Treating Bacterial Infection
参考文献:China]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Triethylamine Solvents: Dichloromethane; 2 H,Rt
标题:Base-Catalyzed Aryl Halide Isomerization Enables The 4-Selective Substitution Of 3-Bromopyridines
作者:Puleo,Thomas R.; Bandar,Jeffrey S.
参考文献:Chemical Science 日期:2020 卷标:11(38) 页码:10517-10522]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Catalysts: 4-(Dimethylamino)Pyridine Solvents: Dichloromethane; 12 H,Rt
标题:Benzoxazolones As Inhibitors Of Inflammasomes And Their Preparation
参考文献:World Intellectual Property Organization]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Triethylamine Solvents: Methanol; 0 °C; 3 H,Rt
标题:Preparation Of (3-Hydroxy-4-Amino-Butan-2-Yl)-3-[2-(Thiazol-2-Yl)Pyrrolidine-1-Carbonyl]Benzamide Derivatives And Related Compounds As Selective Beta-Secretase Inhibitors
参考文献:World Intellectual Property Organization]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Triethylamine Solvents: Methanol; 0 °C; 3 H,Rt
标题:Isophthalamide Compounds Which Inhibit Beta-Secretase Activity And Their Preparation,Pharmaceutical Compositions And Use In The Treatment Of Alzheimer'S Disease
参考文献:World Intellectual Property Organization]

24424-99-5 + 135124-70-8 = 943722-24-5
反应条件:1.1 Reagents: Sodium Bicarbonate Solvents: Tetrahydrofuran,Water; 1 - 3 H,Rt1.2 Reagents: Water; Rt
标题:Preparation Of Substituted Pyridinylpiperazines,Quinolinylpiperazines And Quinoxalinylpiperazines As Gram-Negative Bacteria Efflux Pump Inhibitors
参考文献:World Intellectual Property Organization]

361550-43-8 = 943722-24-5
反应条件:1.1 Reagents: Sodium Hydride Solvents: Tetrahydrofuran; 10 Min,Rt1.2 2 H,Rt1.3 Reagents: Ammonium Chloride Solvents: Water; Rt
标题:Preparation Of Aryloxypyrido[3,4-D]Pyrimidin-4-Ol Derivatives As Histone Demethylase Inhibitors
参考文献:World Intellectual Property Organization]

135124-70-8 = 943722-24-5 [标题:Reaction Conditions
标题:Preparation Of Pyridinylbenzothiazole Derivatives As Dyrk1 Inhibitors
参考文献:World Intellectual Property Organization

📜3-溴吡啶-5-甲醇置于氨,碳酸氢钠,三乙胺体系中,用四氢呋喃,二氯甲烷,水作为反应溶剂,化学反应 16.0H,反应生成 3-(N-Boc-氨基甲基)-5-溴吡啶
参考文献:一类截短侧耳素衍生物,其药物组合物及其合成方法与用途
标题:一类截短侧耳素衍生物,其药物组合物及其合成方法与用途
摘要:本发明涉及一类如下通式(I)所示的截短侧耳素类化合物及其在药学上可接受的盐,其制备方法,以及包含通式(I)所示化合物做为活性成分的组合物.本发明的化合物具有优异的抗菌活性可作为活性物质用于治疗感染性疾病.