专利号:US-6017911-A 优先权日:1996-02-27 标 题 :Pyridonecarboxylic acid derivatives and intermediates for the synthesis thereof 发明人:HORIUCHI NOBUHIKO; YONEZAWA TAKENORI; CHIBA KATSUMI; YOSHIDA HIROAKI 权利人:DAINIPPON PHARMACEUTICAL CO 摘要:This invention relates to pyridonecarboxylic acid derivatives of the following general formula, esters thereof and salts thereof, as well as pharmaceutical preparations containing them. ##STR1## wherein: R is cycloalkyl which may be substituted by halogen, or the like; n X is hydrogen, lower alkyl, amino or the like; n Y is hydrogen or halogen; n A is nitrogen or a group of the formula C--Z in which Z is lower alkoxy that may be substituted by halogen, or the like; n R 1 and R 2 may be the same or different and are each hydrogen or the like; n R 3 is hydrogen or lower alkyl; n R 4 , R 5 , R 6 , R 7 , R 8 and R 9 may be the same or different and are each hydrogen, halogen or lower alkyl; n m is 0 or 1; and n n and p may be the same or different and are each 0 or 1. n This invention also relates to bicyclic amine compounds useful as direct intermediates for the synthesis of the above-described pyridonecarboxylic acid derivatives.
专利号:US-2022389049-A1 优先权日:2019-10-04 标 题:Reversible terminators for dna sequencing and methods of using the same 发明人:JAIN MOTI; ZHOU WEI 权利人:CENTRILLION TECH INC 摘要:The present disclosure provides methods of sequencing polynucleotides and compounds, compositions for sequencing of polynucleotides, and synthesis of such compositions. The chemical compounds include nucleotides and their analogs which possess a sugar moiety comprising a cleavable chemical group capping the 3′-OH group and a base, but without covalently bounded dye. The cleavable chemical group is reactive to form covalent bond(s) with a dye used to confirm the presence of the expected base-pairing. The cleavable chemical group capping the 3′OH group can be removed together with the covalently bounded dye. Furthermore, after the cleavable chemical group is cleaved, the free 3′-OH group can be active in continued elongation. Example chemical compounds according to the present disclosure are shown as Formulas (II) and (V):
专利号:US-12180132-B2 优先权日:2019-07-03 标题:Compositions and methods for synthesis of 2,3-dichloro-1,1,1,2-tetrafluoropropane and 2,3,3,3-tetrafluoropropene 发明人:SUN XUEHUI 权利人:CHEMOURS CO FC LLC 摘要:A method of synthesizing 2,3,3,3-tetrafluoropropene (1234yf) from 2-chloro-3,3,3-trifluoropropene (1233xf). The 2-chloro-3,3,3-trifluoropropene (1233xf) is reacted in the vapor phase, in the presence of a catalyst, at a temperature and pressure sufficient to selectively convert the 2-chloro-3,3,3-trifluoropropene (1233xf) to 2,3,3,3-tetrafluoropropene (1234yf) without the use of antimony-based catalysts.
专利号:US-5855819-A 优先权日:1997-03-27 标 题:Synthesis of conductive polymers in liquid and supercritical CO2 发明人:DESIMONE JOSEPH M; NI YIZENG 权利人:UNIV NORTH CAROLINA 摘要:A method of forming an electrically conductive polymer comprises providing a reaction mixture in carbon dioxide, the reaction mixture comprising at least one monomer and a charge transfer agent. The monomer is then polymerized in the carbon dioxide to form a polymer, and the polymer is doped with the charge transfer agent so that the polymer is an electrically conductive polymer.
专利号:US-8791309-B2 优先权日:2012-12-21 标题 :Synthesis of 3,3,3-trifluoropropyne 发明人:ZHAI YIAN; POSS ANDREW J; SINGH RAJIV R; NALEWAJEK DAVID 权利人:HONEYWELL INT INC 摘要:In accordance with the present invention, processes of synthesizing 3,3,3-trifluoropropyne from 1,3,3,3-tetrafluoropropene, 1-chloro-3,3,3-trifluoropropene, and/or 1,1,1,3,3-pentafluoropropane are provided.
专利号:US-12421182-B2 优先权日:2020-01-23 标 题 :Synthesis of (e)-1,1,1,4,5,5,5-heptafluoro-4-(trifluoromethyl)pent-2-ene 发明人:PETROV VIACHESLAV A; JACKSON ANDREW; PENG SHENG 权利人:CHEMOURS CO FC LLC 摘要:The present application relates to processes of preparing (E)-1,1,1,4,5,5,5-heptafluoro-4-(trifluoromethyl)pent-2-ene.
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