CAS: 55216-11-0; Trimethyl-ß-Cyclodextrin
该化合物是一种化学修正的环十二烯衍生物,其中β-环十二烯的羟基类被甲基化,提高了其在水溶剂和有机溶剂中的溶性.这一修改改善了其宿主-宿主的复杂特性,使其特别有助于在制药和化学应用中溶解氢恐惧化合物.它与本地的β-环环十二烯酯相比,其增加的亲脂性可以更好地与非极分子互动,促进药物的交付,稳定和生物利用率的提高.甲基化结构还减少了热性活动,提高了生物兼容性.三甲基-β-环十二烯在分析化学,配方科学中广泛使用,在分离技术中也广泛用作手性选择剂.
相似化合物
7585-39-9 51166-71-3 68715-56-0物理性质
MSDS等安全信息
上下游产品
CAS号7585-39-9 β-环糊精 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号67-56-1 甲醇合成工艺路线路线简述
📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氨,氢化钾体系中,化学反应生成 三甲基-Beta-环式糊精
参考文献:Freudenberg; Rapp,Chemische Berichte,1936,Vol. 69,P. 2041,2043
标题:Freudenberg; Rapp,Chemische Berichte,1936,Vol. 69,P. 2041,2043
专利信息
专利号:US-2008280855-A1
优先权日:2005-06-22
标 题 :Process For the Production of Intermediates For the Preparation of Tricyclic Benzimidazoles
发明人：CHIESA MARIA VITTORIA; PALMER ANDREAS; BUHR WILM; ZIMMERMANN PETER JAN; BREHM CHRISTOF; SIMON WOLFGANG-ALEXANDER; POSTIUS STEFAN; KROMER WOLFGANG; ZANOTTI-GEROSA ANTONIO
权利人:NYCOMED GMBH
摘要:The invention relates to a process for the synthesis of compounds of the formula 1-a and compounds of the formula 1-b. n n n n n n n n n n The compounds of the formula 1-a and the compounds of the formula 1-b, in which the substituents R1, R2, R3, and Ar have the meanings indicated in the description, are valuable intermediates for the preparation of pharmaceutically active compounds.
专利号:US-2024247311-A1
优先权日:2022-12-22
标题 :Palladium catalyst compositions and methods for sequencing by synthesis
发明人：PEDROSO CASSIO; PANIGRAHI ADYASHA; MARIANI ANGELICA; CARVER ADAM; HOURS RAPHAËLLE; CHANDRACHUD PREETI; FRANCAIS ANTOINE; APSUNDE TUSHAR; HATTINGH KATHRYN; BEECH TIMOTHY; SOLIS DANIEL; LAWRENCE ELLIOT J
权利人:ILLUMINA INC
摘要:The present application relates to palladium catalyst composition and uses in sequencing by synthesis. In particular, the Pd catalyst composition comprises one or more macrocycles (e.g., cyclodextrin or analogs thereof) as additives for improving thermal or oxidative stability of the active Pd(0) species.
专利号:US-2024327909-A1
优先权日:2023-03-30
标题 :Compositions and methods for nucleic acid sequencing
发明人：WU XIAOLIN; GATTI LAFRANCONI PIETRO; BEECH TIMOTHY; BRAVIN CARLO; MACKWORTH BENEDICT; TONGUE THOMAS; BALDING PHILIP
权利人:ILLUMINA INC
摘要:Embodiments of the present application relates to methods and compositions for increasing fluorescent dye signal intensity during sequencing by synthesis. In particular, the compositions and methods described herein involve the use aqueous scan mixtures including one or more water-soluble macrocycles that can form host-guest complexes with the dyes.
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主要参考文献
[参考文献]: Alessandra Ammazzalorso, Et Al. Enantiomeric Separation Of Gemfibrozil Chiral Analogues By Capillary Electrophoresis With Heptakis(2,3,6-Tri-O-Methyl)-Beta-Cyclodextrin As Chiral Selector. J Chromatogr A. 2005 Sep 23;1088(1-2):110-20.[参考文献]: Anna Rocco, Et Al. Enantiomeric Separation Of Acidic Compounds By Nano-Liquid Chromatography With Methylated-Beta-Cyclodextrin As A Mobile Phase Additive. J Sep Sci. 2009 May;32(10):1696-703.
[参考文献]: Anne-Catherine Servais, Et Al. Application Of Dual Cyclodextrin Systems In Capillary Electrophoresis Enantioseparations. Methods Mol Biol. 2013:970:289-95.
[参考文献]: Frantzeska Tsorteki, Et Al. Inclusion Compounds Of Plant Growth Regulators In Cyclodextrins. V. 4-Chlorophenoxyacetic Acid Encapsulated In Beta-Cyclodextrin And Heptakis(2,3,6-Tri-O-Methyl)-Beta-Cyclodextrin. Acta Crystallogr B. 2005 Apr;61(Pt 2):207-17.
[参考文献]: Madhurima Jana, Et Al. Low-Frequency Vibrational Spectrum Of Water Around Cyclodextrin And Its Methyl-Substituted Derivatives. Langmuir. 2010 Sep 7;26(17):14097-102.
合成参考文献
参考文献:10.1007/978-1-62703-263-6_3
摘要:Schurig V, Kreidler D. Gas-chromatographic enantioseparation of unfunctionalized chiral hydrocarbons: an overview. Methods Mol Biol. 2013;970():45–67. doi: 10.1007/978-1-62703-263-6_3.
参考文献:10.1007/978-1-62703-263-6_18
摘要:Servais AC, Fillet M. Application of dual cyclodextrin systems in capillary electrophoresis enantioseparations. Methods Mol Biol. 2013;970():289–95. doi: 10.1007/978-1-62703-263-6_18.
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