CAS: 548-98-1; 10,13-Dimethyl-17-[pentan-2-Yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[a]Phenanthrene

专利信息

专利号:WO-2021214685-A1
优先权日:2020-04-21
标 题:Method for the synthesis of a cholane derivative
发明人：GALDI GIANLUCA; SACCO PAOLO; PIATEK ANNA MARIA; VESTRI ALESSANDRO
权利人:BAR PHARMACEUTICALS SOC A RESPONSABILITA LIMITATA
摘要:The present invention refers to a method for the preparation of a compound of formula (I).

专利号:US-9382288-B2
优先权日:2010-10-06
标题 :Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action
发明人：BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO
权利人:BECKER KATJA; KRIEG REIMAR; SCHÖNECKER BRUNO; UNIV GIESSEN JUSTUS LIEBIG
摘要:The present invention relates to compounds derived from steroids of the general formula (I) n nwherein L represents a linker and R # represents a steroid residue, the use of compounds of the general formula (I) in medicine and for the prophylaxis and/or the treatment of infectious diseases. Furthermore described are pharmaceutical compositions containing at least one compound of the general formula (I). A further aspect of the invention relates to the synthesis of said compounds of the general formula (I).

专利号:WO-2024170915-A1
优先权日:2023-02-16
标题 :Use of tandem facial amphiphiles for protein expression
发明人：ADIRAJ IYER MAHESHWAR; SLOMINSKI LUKE M; SPICE ALEX J; VU KHANH; ZANZOTTO ANDREA
权利人:NUCLERA LTD
摘要:Provided herein are improved reagent compositions for cell-free protein synthesis. Particularly provided are improved aqueous droplet compositions having a tandem facial amphiphiles, and their use in methods of cell-free protein synthesis, optimised cell-free protein synthesis (CFPS) reagents, and methods for optimising CFPS reagents to increase protein expression yields and reduce biofouling. The methods are applicable to cell-free protein expression on a microfluidic device having hydrophobic surfaces.

专利号:US-2018312534-A1
优先权日:2015-10-16
标题:Fluorescent anticancer platinum drugs
发明人：SARKAR ARINDAM; MANDAL SWADHIN KUMAR; SENGUPTA ANIRUDDHA; BISWAS GOUTAM; DUTTA PRADIP; SHARMA RUPALI; RAJ JUSTIN PAUL; SURYAVANSHI HEMANT; KUMARI SMITA
权利人:INVICTUS ONCOLOGY PVT LTD
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to fluorescent platinum based compounds. The disclosure further relates to synthesis of said fluorescent platinum based compounds, nanoparticles and compositions comprising said fluorescent platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by the fluorescence changes between aforesaid platinum based compounds and corresponding free ligands, nanoparticles and compositions.

专利号:US-10730899-B2
优先权日:2013-06-14
标 题 :Lipid-based platinum compounds and nanoparticles
发明人：SENGUPTA SHILADITYA; ROY MONIDEEPA; SARKAR ARINDAM; HOSSAIN SK SAMAD; SENGUPTA ANIRUDDHA; DUTTA PRADIP; ANSARI AASIF
权利人:AKAMARA THERAPEUTICS INC
摘要:The present disclosure is in relation to the field of nanotechnology and cancer therapeutics. In particular, the present disclosure relates to platinum based compounds comprising platinum moiety, linker moiety and lipid moiety and corresponding nanoparticles thereof. The disclosure further relates to synthesis of said platinum based compounds, nanoparticles and compositions comprising said platinum based compounds/nanoparticles. The disclosure also relates to methods of managing cancer by employing aforesaid carbene compounds, platinum based compounds, nanoparticles and compositions thereof.

专利号:US-9295677-B2
优先权日:2008-02-26
标题 :Polyhydroxylated bile acids for treatment of biliary disorders
发明人：LING VICTOR; WANG RENXUE; SHEPS JONATHAN AHAB
权利人:LING VICTOR; WANG RENXUE; SHEPS JONATHAN AHAB; QING BILE THERAPEUTICS INC
摘要:The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2α,3α,7α,12α-tetrahydroxy-5β-cholanoic acid and 3α.4α,7α,12α-tetrahydroxy-5β-cholanoic acid are disclosed, uses thereof and synthesis thereof.