专利号:US-4975441-A 优先权日:1988-03-23 标 题:Lactams, their synthesis and use in cosmetic compositions 发明人:GIBSON WALTER T 权利人:UNILEVER PATENT HOLDINGS 摘要:A composition suitable for topical application to mammalian skin or hair for inducing, maintaining or increasing hair growth comprises: (i) a chemical inhibitor of glycosidase activity chosen from lactams having the structure: where A<1> and A<6> are -H, -CH3, - @@0, -CH2OT or @@@0 A<1> and A<6> being the same or different, and at least one of which being the group: @ @@o in a lactam ring; and where Q is -OT min , -NHT min or a lactam linkage to A<1> or A<6>; the Q groups being the same or different, and at least one of which is involved in a lactam linkage; and where T is the same or different and is chosen from -H, -CpH2p+1 or a metal ion, T min is -H or -COCpH2p+1, and p is an integer of from 1 to 22; provided that: where any of the Q groups is -OT min or -NHT min , then that group or groups can be of either stereochemical configuration with respect to the plane of the ring; and (ii) a cosmetically acceptable vehicle for the chemical inhibitor. Certain novel lactams are also claimed.
摘要:Compound: Polyquaternium 11 摘要:International Journal of Toxicology 24(Suppl. 1):1-102, 2005 摘要:Journal of the American College of Toxicology 2(5):161-178, 1983