CAS: 5000-46-4; 1-(Methylsulfonyl)Propan-2-One

相似化合物

1977-38-4 86453-13-6 91313-63-2

上下游产品

methylsulfanyl-acetone methyl methanesulfinate chloroacetone 3-methanesulfonyl-pentane-2,4-dione4-(2',4'-dichlorophenyl)-3-methylsulfonyl-but-3-en-2-one 6-bromo-3-methanesulfonyl-2-methyl-4-phenyl-quinoline 3-methanesulfonyl-2-methyl-4-phenyl-1H-pyrrole

📜1-甲基硫代-2-丙酮置于sodium Tungstate (Vi) Dihydrate,双氧水体系中,用 甲醇,水 作为反应溶剂,以100%的收率获得产物甲磺酰乙酮
参考文献:四钼酸四烷基铵 催化剂 用于选择性 氧化作用 硫化物转化为亚砜 过氧化氢
标题:四钼酸四烷基铵 催化剂 用于选择性 氧化作用 硫化物转化为亚砜 过氧化氢
摘要:四钼酸四烷基铵 催化剂 成功应用于选择性 氧化作用 含30%水溶液的各种硫化物转化为亚砜 过氧化氢在温和的反应条件下作为氧化剂,收率为94-100%,选择性为95-100%.这八钼酸盐 催化剂 显示高 催化活性 以高比例的底物 催化剂 (最高10000:1)且可回收,功能活跃 团体,包含 羟 团体和c C键,在氧化作用.
DOI:10.1039/b912521N

专利信息

专利号:US-8633182-B2
优先权日:2012-05-30
标题:Indanyloxyphenylcyclopropanecarboxylic acids
发明人：HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN
权利人:HAMPRECHT DIETER; FRATTINI SARA; LINGARD IAIN; PETERS STEFAN; BOEHRINGER INGELHEIM INT
摘要:The present invention relates to compounds of general formula I, n nwherein the groups R 1 , R 2 , R 3 , m and n are defined as in claim 1 , which have valuable pharmacological properties, in particular bind to the GPR40 receptor and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.

专利号:US-4072716-A
优先权日:1971-12-24
标 题:Bicycloalkane derivatives
发明人：SAUER GERHARD; HAUSER HELMUT; HAFFER GREGOR; RUPPERT JUERGEN; EDER ULRICH; WIECHERT RUDOLF
权利人:SCHERING AG
摘要:Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R 1 is lower alkyl, X is carbonyl or free or etherified hydroxymethylene, and Y is --S--R 2 , --SO m --R 2 , or ##STR2## wherein m is 1 or 2, R 2 is alkyl, R 3 is hydrogen or lower alkyl, R 4 is aliphatic acyl and Z is nitro, lower alkanoyl, lower alkylsulfinyl, or lower alkylsulfonyl are useful intermediates in the total synthesis of steroids. The compounds are prepared by reacting a corresponding compound lacking the CH 2 Y substituent with formaldehyde and a mercaptan or a sulfinic acid, followed if desired by oxidation and optional salt condensation.

专利号:US-4051188-A
优先权日:1971-12-24
标题 :Novel bicycloalkane derivatives and the production thereof
发明人：SAUER GERHARD; HAUSER HELMUT; HAFFER GREGOR; RUPPERT JUERGEN; EDER ULRICH; WIECHERT RUDOLF
权利人:SCHERING AG
摘要:Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R 1 is lower alkyl, X is carbonyl or a free or etherified hydroxymethylene, and Y is --S--R 2 , --SO m --R 2 , or ##STR2## wherein m is 1 or 2, R 2 is aryl or aralkyl, R 3 is hydrogen or lower alkyl, R 4 is phenyl optionally substituted with lower alkoxy or benzyloxy, and Z is nitro, lower alkanoyl, lower alkylsulfinyl, or lower alkylsulfonyl, are useful intermediates in the total synthesis of steroids. The compounds are prepared by reacting a corresponding compound lacking the CH 2 Y substituent with formaldehyde and a mercaptan or a sulfinic acid, followed if desired by oxidation and optional salt condensation.

专利号:US-2024308969-A1
优先权日:2023-02-10
标题:Inverse electron demand diels-alder type heterocycle synthesis with 1,2,3-triazine 1-oxides
发明人：DOYLE MICHAEL P; DE ANGELIS LUCA; BISWAS SOUMEN; RIVERA GILDARDO
权利人:UNIV TEXAS
摘要:Embodiments are directed to practical strategies for inverse electron demand Diels-Alder (IEDDA) reactions with 1,2,3-triazine 1-oxides. These bench stable N-oxides undergo unprecedented nucleophilic addition with dienophile to form polysubstituted heteroarenes in high yield. Rapid at room temperature, these catalyst free reactions offer a diversity of structural modifications for heterocyclic syntheses.

专利号:US-4008253-A
优先权日:1971-12-24
标题 :Bicycloalkanes
发明人：SAUER GERHARD; HAUSER HELMUT; HAFFER GREGOR; RUPPERT JURGEN; EDER ULRICH; WIECHERT RUDOLF
权利人:SCHERING AG
摘要:Bicycloalkane derivatives of the formula ##STR1## WHEREIN N IS 1 OR 2, R 1 is lower alkyl, X is free or ketalized carbonyl or a free, esterified, or etherified hydroxymethylene, and Y is --S--R 2 , --SO m --R 2 , or ##STR2## wherein m is 1 or 2, R 2 is alkyl, aryl, or aralkyl, R 3 is hydrogen or lower alkyl, R 4 is alkoxycarbonyl, or acyl or phenyl optionally substituted with lower alkoxy or benzyloxy- or acyloxy; and Z is nitrile, nitro, lower alkoxycarbonyl, lower alkanoyl, lower alkylsulfinyl, or lower alkylsulfonyl are useful intermediates in the total synthesis of steroids. The compounds are prepared by reacting a corresponding compound lacking the CH 2 Y substituent with formaldehyde and a mercaptan or a sulfinic acid, followed if desired by oxidation and optional salt condensation.

专利号:US-4202991-A
优先权日:1971-12-24
标 题:Novel bicycloalkane derivatives and the production thereof
发明人：EDER ULRICH; HAFFER GREGOR; HAUSER HELMUT; RUPPERT JUERGEN; SAUER GERHARD; WIECHERT RUDOLF
权利人:SCHERING AG
摘要:Bicycloalkane derivatives of the formula ##STR1## wherein n is 1 or 2, R 1 is lower alkyl, Acyl is alkanoyl, and Y is --S--R 2 , --SO m --R 2 , or ##STR2## wherein m is 1 or 2, R 2 is alkyl, R 3 is hydrogen or lower alkyl, R 4 is acyl or phenyl optionally substituted with lower alkoxy, benzyloxy or alkanoyloxy; and Z is nitro, lower alkoxycarbonyl, lower alkanoyl, lower alkylsulfinyl, or lower alkylsulfonyl are useful intermediates in the total synthesis of steroids. The compounds are prepared by reacting a corresponding compound lacking the CH 2 Y substituent with formaldehyde and a mercaptan or sulfinic acid, followed if desired by oxidation and optional salt condensation.