CAS: 4160-52-5; 1-(P-Tolyl)Butan-1-One

上下游产品

1-对甲苯基丁烷-1,3-二酮 1-(4-Methylphenyl)Butan-1,3-Dione 4023-79-4
环丙基(4-甲基苯基)-甲酮 Cyclopropyl-P-Tolyl-Methanone 7143-76-2
1-(4-甲基苯基)丁-2-烯-1-酮 (E)-1-(4-Methylphenyl)-2-Buten-1-One 3837-95-4

对甲基苯甲醛置于戴斯-马丁氧化剂体系中,用 四氢呋喃,乙醚,二氯甲烷 作为反应溶剂,化学反应 16.0H,反应生成 4-甲基苯丁酮
参考文献:通过双酶还原级联合成光学活性的 Syn-和 Anti-Chlorohydrins
标题:通过双酶还原级联合成光学活性的 Syn-和 Anti-Chlorohydrins
摘要:设计并优化了双酶级联反应,从相应的 1-Aryl-2-Chlorobut-2-En-1-Ones 开始获得对映体纯的氯代醇.对于这些 α-氯烯酮的合成,开发了一个两步序列,包括相应醛与 3-二氯丙-1-烯的烯丙基化,然后氧化和进一步异构化.涉及烯还原酶 (Ered) 和醇脱氢酶 (Adh) 的选择性协同催化系统在温和的反应条件下以优异的转化率(高达 >99%)和选择性(高达 >99:1 的非对映异构比)提供了所需的光学活性氯醇(Dr),>99% 对映体过量 (Ee)).
DOI:10.1021/acs.Orglett.2C02592

专利信息

专利号:US-7517828-B2
优先权日:2003-04-25
标 题 :Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst
发明人：AKIYAMA TAKAHIKO
权利人:TOAGOSEI CO LTD
摘要:A compound usable as an asymmetric synthesis catalyst which can be easily synthesized without using any metal such as a lanthanoid group element; a method of asymmetric synthesis with the compound; and a chiral compound obtained by the asymmetric synthesis method. A Broensted acid is used as a catalyst in asymmetric synthesis, the chiral Broensted acid being represented by formula (1) below or formula (3) below. The asymmetric synthesis method employs the catalyst. Asymmetric synthesis with the catalyst gives a chiral compound.

专利号:CN-105906591-A
优先权日:2016-04-22
标 题:Synthesis of 2-amino-γ-butyrolactone hydrochloride

专利号:US-2006276329-A1
优先权日:2003-04-25
标题:Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst

专利号:EP-1623971-A1
优先权日:2003-04-25
标 题:Asymmetric-synthesis catalyst based on chiral broensted acid and method of asymmetric synthesis with the catalyst