CAS: 37693-18-8; 4-Chlorobutyl Carbonochloridate

该化合物是一种活性氯仿酯酯,通常用作有机合成的中间体,其主要优点包括能够作为高效的烷基剂,促进将4-氯丁基组引入目标分子;该化合物在双极联动反应和制药中间体的准备方面特别有用;其两功能-氯基和氯基基组--在建造复杂的分子结构方面具有多种用途;该试剂由于对水的敏感性,通常在水性条件下处理;适当的储存和处理对于保持其合成应用的回活动性和稳定性至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

CAS号75-44-5 光气 | CAS号928-51-8 4-氯-1-丁醇 | CAS号946-02-1 苯甲酸4-氯丁酯 | CAS号63981-83-9 4-carbamoyloxyb...

合成工艺路线路线简述

    📜光气,4-氯丁醇 反应生成 4-氯丁基氯甲酸酯
    参考文献:Reppe Et Al.,Justus Liebigs Annalen Der Chemie,1955,Vol. 596,P. 65
    标题:Reppe Et Al.,Justus Liebigs Annalen Der Chemie,1955,Vol. 596,P. 65

    海关参考信息

    专利信息


    专利号:US-7294719-B2
    优先权日:2004-10-26
    标题 :Synthesis of amino acid, N-carboxyanhydrides
    发明人:CARUBIA JOHN MICHAEL; WEAVER THOMAS MARK; PONNUSAMY ETTIGOUNDER
    权利人:SIGMA ALDRICH CO
    摘要:A process for producing N-carboxyanhydrides is disclosed. The process produces N-carboxyanhydrides as a product and HCl as a by-product. The HCl by-product is purged from the reaction mixture by passing a purge gas through the reaction mixture as a carbonylation reagent is reacting with an amino acid or a salt thereof. The N-carboxyanhydrides produced by this process have a relatively lower chloride impurity content, relatively higher yields can be achieved, and the N-carboxyanhydrides can be produced on a larger scale.

    专利号:US-2006106229-A1
    优先权日:2004-10-26
    标题 :Synthesis of amino acid, N-carboxyanhydrides

    专利号:JP-2008518032-A
    优先权日:2004-10-26
    标题 :Synthesis of amino acid N-carboxyanhydride

    专利号:CA-2584311-C
    优先权日:2004-10-26
    标题:Synthesis of amino acid, n-carboxyanhydrides

    专利号:WO-2006047703-A2
    优先权日:2004-10-26
    标 题:Synthesis of amino acid, n-carboxyanhydrides

    专利号:EP-1809616-A2
    优先权日:2004-10-26
    标题 :Synthesis of amino acid, n-carboxyanhydrides

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知