专利号:US-11719709-B2 优先权日:2020-02-14 标题 :Water soluble polymer surfactant for synthesis of functionalized polystyrene nanobeads towards detection of bilirubin in human serum 发明人:MAKKAD SARABJOT KAUR; SYAMAKUMARI ASHA 权利人:COUNCIL SCIENT IND RES 摘要:The present invention provides a water soluble polymer surfactant (PS-DGlu) of formula I which is utilized for synthesis of functionalized polystyrene nanobead covalently incorporating (oligo) p-phenylenevinylene (OPV) nanosensor (PSG-OPV-n) which in turn is useful for the detection of bilirubin in human serum. The present invention further provides a process for the preparation of the water soluble polymer surfactant (PS-DGlu) of formula (I) and a mini emulsion polymerization process for the synthesis of PSG-OPV-n.wherein, n is 30-50.The PSG-OPV-n nanosensor beads show selectivity towards detection of bilirubin in presence of interferences such as glucose, sucrose, metal ions, cholesterol, and biliverdin with limit of detection of 20 nM. Ultimately, the invention also provides a kit for visual detection of bilirubin in human serum.
专利号:WO-2024163733-A1 优先权日:2023-02-01 标题:Electrochemical synthesis with redox stable nucleotides 发明人:WU TIANDI; LACKEY JEREMY; LIN YANYOU; PITSCH STEFAN 权利人:TWIST BIOSCIENCE CORP 摘要:Provided herein are compositions, devices, systems and methods for constructing and storing polynucleotides encoding information with redox resistant bases. The compositions, devices, systems, and methods described herein provide for storage or synthesis of a library comprising a plurality of polynucleotides with one or more redox resistance bases. Further provided herein are methods to increase DNA synthesis yield and fidelity.
专利号:WO-2024168123-A1 优先权日:2023-02-09 标 题 :Synthesis of core 2 o-sialyl lewis-x polysaccharides 发明人:CHAIKOF ELLIOT; DHAKAL BIBEK; MANDHAPATI APPI; ERADI PRADHEEP 权利人:BETH ISRAEL DEACONESS MEDICAL CT INC 摘要:Provided herein are methods and compounds useful in the preparation of Core 2 O -sialyl Lewis x polysaccharides including compounds of Formula (C).
专利号:CN-107829105-B 优先权日:2017-11-16 标题:A kind of method for electrochemical synthesis of α-acyloxy ketone
专利号:CN-113861119-B 优先权日:2021-11-23 标题 :A method for cobalt-catalyzed synthesis of quinoline and quinazoline compounds
专利号:CN-115536609-B 优先权日:2022-08-12 标题 :A kind of synthesis method of hydrogen isotope labeled vortioxetine
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合成参考文献
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